Novel insights into the pharmacology of flavonoids

B Romano, E Pagano, V Montanaro… - Phytotherapy …, 2013 - Wiley Online Library
Flavonoids are widely distributed secondary metabolites and currently consumed in large
amounts in the daily diet. In this article, some of the most recent developments in flavonoid …

Investigating ROS sources in male infertility: a common end for numerous pathways

G Lavranos, M Balla, A Tzortzopoulou, V Syriou… - Reproductive …, 2012 - Elsevier
Reactive oxygen species (ROS) are active byproducts of aerobic metabolism. Although they
are constantly produced during normal cellular activities in the mitochondria, their action is …

Potential of natural products as radioprotectors and radiosensitizers: Opportunities and challenges

J Yi, J Zhu, C Zhao, Q Kang, X Zhang, K Suo, N Cao… - Food & Function, 2021 - pubs.rsc.org
Natural products can be used as natural radiosensitizers and radioprotectors, showing
promising effects in cancer treatments in combination with radiotherapy, while reducing …

The effect of Lycium barbarum polysaccharides on the male rats׳ reproductive system and spermatogenic cell apoptosis exposed to low-dose ionizing irradiation

Q Luo, J Li, X Cui, J Yan, Q Zhao, C Xiang - Journal of ethnopharmacology, 2014 - Elsevier
Ethnopharmacological relevance: Lycium barbarum, a Solanaceous defoliated shrubbery,
has been used as a kind of traditional Chinese herbal medicines for thousands of years …

Phytoestrogen genistein hinders ovarian oxidative damage and apoptotic cell death-induced by ionizing radiation: co-operative role of ER-β, TGF-β, and FOXL-2

YH Haddad, RS Said, R Kamel, EME Morsy… - Scientific Reports, 2020 - nature.com
Radiotherapy is a well-known cause of premature ovarian failure (POF). Therefore, we
investigated the molecular influence of genistein (GEN) on the ovarian reserve of rats …

Wuzi Yanzong pill, a Chinese polyherbal formula, alleviates testicular damage in mice induced by ionizing radiation

HJ Ji, DM Wang, YP Wu, YY Niu, LL Jia, BW Liu… - … and alternative medicine, 2016 - Springer
Abstract Background Chinese medicine Wuzi Yanzong pill (WZYZP) was firstly documented
in ancient Chinese medical works “She Sheng Zhong Miao Fang” by Shi-Che Zhang in 1550 …

Reproductive aging and telomeres: Are women and men equally affected?

L Chico-Sordo, I Cordova-Oriz, AM Polonio… - Mechanisms of Ageing …, 2021 - Elsevier
Successful reproduction is very important for individuals and for society. Currently, the
human health span and lifespan are the object of intense and productive investigation with …

Mechanism and therapeutic window of a genistein nanosuspension to protect against hematopoietic-acute radiation syndrome

MR Landauer, AJ Harvey, MD Kaytor… - Journal of radiation …, 2019 - academic.oup.com
There are no FDA-approved drugs that can be administered prior to ionizing radiation
exposure to prevent hematopoietic–acute radiation syndrome (H-ARS). A suspension of …

A novel oral formulation of BIO 300 confers prophylactic radioprotection from acute radiation syndrome in mice

VK Singh, OO Fatanmi, SY Wise… - … journal of radiation …, 2022 - Taylor & Francis
Purpose Exposure to high doses of ionizing radiation can result in hematopoietic acute
radiation syndrome (H-ARS) and delayed effects of acute radiation exposure (DEARE) …

Low-dose-rate radiation exposure leads to testicular damage with decreases in DNMT1 and HDAC1 in the murine testis

EJ Gong, IS Shin, TG Son, K Yang… - Journal of Radiation …, 2014 - academic.oup.com
This study examined the effects of continuous low-dose-rate radiation exposure (3.49
mGy/h) of gamma rays on mice testicles. C57BL/6 mice were divided into sham and …