Quercetin derivatives: Drug design, development, and biological activities, a review

SR Alizadeh, MA Ebrahimzadeh - European journal of medicinal chemistry, 2022 - Elsevier
More studies are needed to develop new drugs for problems associated with drug
resistance and unfavorable side effects. The natural flavonoid of quercetin revealed a wide …

Neuroprotective activities of curcumin in Parkinson's disease: a review of the literature

EE Nebrisi - International journal of molecular sciences, 2021 - mdpi.com
Parkinson's disease (PD) is a slowly progressive multisystem disorder affecting
dopaminergic neurons of the substantia nigra pars compacta (SNpc), which is characterized …

Curcumin, an active component of turmeric (Curcuma longa), and its effects on health

B Kocaadam, N Şanlier - Critical reviews in food science and …, 2017 - Taylor & Francis
Turmeric (Curcuma longa) is a type of herb belonging to ginger family, which is widely
grown in southern and south western tropical Asia region. Turmeric, which has an …

[HTML][HTML] New agents that target senescent cells: the flavone, fisetin, and the BCL-XL inhibitors, A1331852 and A1155463

Y Zhu, EJ Doornebal, T Pirtskhalava… - Aging (Albany …, 2017 - ncbi.nlm.nih.gov
Senescent cells accumulate with aging and at sites of pathology in multiple chronic
diseases. Senolytics are drugs that selectively promote apoptosis of senescent cells by …

Nrf2–ARE pathway: an emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases

I Buendia, P Michalska, E Navarro, I Gameiro… - Pharmacology & …, 2016 - Elsevier
Neurodegenerative diseases (NDDs) are predicted to be the biggest health concern in this
century and the second leading cause of death by 2050. The main risk factor of these …

The potential of flavonoids for the treatment of neurodegenerative diseases

P Maher - International journal of molecular sciences, 2019 - mdpi.com
Neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD),
Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS), currently affect more …

Curcumin's nanomedicine formulations for therapeutic application in neurological diseases

B Salehi, D Calina, AO Docea, N Koirala… - Journal of Clinical …, 2020 - mdpi.com
The brain is the body's control center, so when a disease affects it, the outcomes are
devastating. Alzheimer's and Parkinson's disease, and multiple sclerosis are brain diseases …

Discovery of curcumin, a component of golden spice, and its miraculous biological activities

SC Gupta, S Patchva, W Koh… - Clinical and …, 2012 - Wiley Online Library
Curcumin is the active ingredient of the dietary spice turmeric and has been consumed for
medicinal purposes for thousands of years. Modern science has shown that curcumin …

Curcumin and its derivatives: their application in neuropharmacology and neuroscience in the 21st century

WH Lee, CY Loo, M Bebawy, F Luk… - Current …, 2013 - ingentaconnect.com
Curcumin (diferuloylmethane), a polyphenol extracted from the plant Curcuma longa, is
widely used in Southeast Asia, China and India in food preparation and for medicinal …

Pharmacokinetic, pharmacodynamic and formulations aspects of Naringenin: An update

R Joshi, YA Kulkarni, S Wairkar - Life sciences, 2018 - Elsevier
Phenolic compounds constitute one of the important classes of secondary metabolites in the
plants. Flavonoids are primary phenolic compounds found in natural drugs. Naringenin is a …