Toxicity testing relies heavily on animals, especially rodents as part of the non-clinical
laboratory testing of substances. However, the use of mammalians and the number of …

Caesalpinia ferrea C. Mart., popularly known as “Jucá” or “Pau-ferro”, belongs to the
Fabaceae family, and is classified as a native and endemic species in Brazil. Numerous …

The zebrafish (Danio rerio) is an emerging model system in several research areas
worldwide, especially in the Global South. In this context, the present study revised the …

Because of essential role in homeostasis of the body fluid and excretion of wastes, kidney
damage can lead to severe impacts on health and survival of humans. For most chemicals …

Abstract Ethnopharmacological relevance Although the Traditional Chinese Medicine (TCM)
prescription of Danggui Shaoyao San (DSS) presents substantial clinical efficacy and …

Abstract Ethnopharmacological relevance In Brazil, ethnopharmacological studies show that
Libidibia ferrea (Mart. ex Tul.) LP Queiroz is commonly used in folk medicine as an …

The native flora of Brazil covers a large biodiversity of plants, some of which have important
pharmacological properties. Ethnobotanical studies have established that the folk use of …

Plant extracts are increasingly recognized as potential prophylactic agents in poultry
production due to their diverse bioactive properties. This study investigated the …

The species Trattinnickia rhoifolia Willd,(T. rhoifolia), which belongs to the Burseraceae
family, is widely used in ethnopharmacological cultural practices by traditional Amazonian …

Abstract Context The botanical species Bauhinia guianensis Aublet (Leguminosae-
Cercidoideae) is traditionally used in the Amazon for medicinal purposes. Objective The …