[HTML][HTML] Exosomal circRNA-100338 promotes hepatocellular carcinoma metastasis via enhancing invasiveness and angiogenesis

XY Huang, ZL Huang, J Huang, B Xu… - Journal of Experimental …, 2020 - Springer
Background Exosomes play crucial roles in regulating the crosstalk between normal and
cancer cells in the tumor microenvironment, and in regulating cancer proliferation, migration …

Activation of autophagy by sitagliptin attenuates cadmium-induced testicular impairment in rats: Targeting AMPK/mTOR and Nrf2/HO-1 pathways

HH Arab, AM Gad, E Reda, R Yahia, AH Eid - Life Sciences, 2021 - Elsevier
Abstract Aims Cadmium (Cd) is a prevalent environmental contaminant that incurs
deleterious health effects, including testicular impairment. Sitagliptin, a selective dipeptidyl …

Cadmium as a male reproductive toxicant and natural and non-natural ways to tackle it: a review

UR Wanjari, AV Gopalakrishnan - Environmental Science and Pollution …, 2024 - Springer
Cadmium (Cd) is a naturally occurring environmental pollutant, a toxic substance that
causes oxidative stress. According to epidemiological studies, the data suggested that …

[HTML][HTML] Sperm cohort-specific zinc signature acquisition and capacitation-induced zinc flux regulate sperm-oviduct and sperm-zona pellucida interactions

K Kerns, M Sharif, M Zigo, W Xu, LE Hamilton… - International journal of …, 2020 - mdpi.com
Building on our recent discovery of the zinc signature phenomenon present in boar, bull,
and human spermatozoa, we have further characterized the role of zinc ions in the …

Retracted: Curcumin inhibits the survival and metastasis of prostate cancer cells via the Notch‐1 signaling pathway

J Yang, C Wang, Z Zhang, X Chen, Y Jia, B Wang… - Apmis, 2017 - Wiley Online Library
Prostate cancer is one of the most common malignancies in men, and it urgently demands
precise interventions that target the signaling pathways implicated in its initiation …

Cadmium exposure is associated with testosterone levels in men: A cross-sectional study from the China National Human Biomonitoring

Y Qiu, Y Lv, M Zhang, S Ji, B Wu, F Zhao, Y Qu, Q Sun… - Chemosphere, 2022 - Elsevier
Background Sex hormone disorders can cause adverse health consequences. While
experimental data suggests that cadmium (Cd) disrupts the endocrine system, little is known …

Inotodiol inhibits cells migration and invasion and induces apoptosis via p53-dependent pathway in HeLa cells

SD Zhang, L Yu, P Wang, P Kou, J Li, LT Wang… - Phytomedicine, 2019 - Elsevier
Background Inonotus obliquus, namely as Chaga mushroom, is a medicinal and edible
fungus, which is widely used in food and medical fields. Inotodiol, a natural lanostane-type …

Cadmium induces matrix metalloproteinase-9 expression via ROS-dependent EGFR, NF-кB, and AP-1 pathways in human endothelial cells

S Lian, Y Xia, PN Khoi, TT Ung, HJ Yoon, NH Kim… - Toxicology, 2015 - Elsevier
Cadmium (Cd), a widespread cumulative pollutant, is a known human carcinogen,
associated with inflammation and tumors. Matrix metalloproteinase-9 (MMP-9) plays a …

[HTML][HTML] Opposite functions of GSN and OAS2 on colorectal cancer metastasis, mediating perineural and lymphovascular invasion, respectively

JC Kim, YJ Ha, KH Tak, SA Roh, YH Kwon, CW Kim… - PloS one, 2018 - journals.plos.org
The present study aimed to identify molecules associated with lymphovascular invasion
(LVI) and perineural invasion (PNI) and to examine their biological behavior in colorectal …

Metformin inhibits the proliferation, metastasis, and cancer stem-like sphere formation in osteosarcoma MG63 cells in vitro

X Chen, C Hu, W Zhang, Y Shen, J Wang, F Hu, P Yu - Tumor Biology, 2015 - Springer
Metformin is an oral drug that has been widely used to treat type 2 diabetes mellitus.
Interestingly, accumulated evidence indicate that metformin may reduce the risk of cancer in …