Nanocarriers for targeted drug delivery in the vascular system: Focus on endothelium
X Cong, Z Zhang, H Li, YG Yang, Y Zhang… - Journal of …, 2024 - Springer
Endothelial cells (ECs) are pivotal in maintaining vascular health, regulating hemodynamics,
and modulating inflammatory responses. Nanocarriers hold transformative potential for …
and modulating inflammatory responses. Nanocarriers hold transformative potential for …
Advances in nanotherapeutic strategies for Huntington's disease: Design, delivery, and neuroprotective mechanisms
Huntington's Disease (HD) is a severe neurodegenerative disorder lacking effective
diagnostic and treatment options. However, there is increasing interest in the potential of …
diagnostic and treatment options. However, there is increasing interest in the potential of …
Targeting human endothelial cells with glutathione and alanine increases the crossing of a polypeptide nanocarrier through a blood–brain barrier model and entry to …
Nanoparticles (NPs) are the focus of research efforts that aim to develop successful drug
delivery systems for the brain. Polypeptide nanocarriers are versatile platforms and combine …
delivery systems for the brain. Polypeptide nanocarriers are versatile platforms and combine …
Co-delivery of paclitaxel and etoposide prodrug by human serum albumin and PLGA nanoparticles: synergistic cytotoxicity in brain tumour cells
T Kovshova, S Mantrov, S Boiko… - Journal of …, 2023 - Taylor & Francis
The aims of this study were to develop co-delivery systems of paclitaxel (PTX) and etoposide
prodrug (4'-O-benzyloxycarbonyl-etoposide, ETP-cbz) based on non-cross-linked human …
prodrug (4'-O-benzyloxycarbonyl-etoposide, ETP-cbz) based on non-cross-linked human …
Recent advancements on in vitro blood-brain barrier model: A reliable and efficient screening approach for preclinical and clinical investigation
Introduction The efficiency of brain therapeutics is greatly hindered by the blood-brain
barrier (BBB). BBB's protective function, selective permeability, and dynamic functionality …
barrier (BBB). BBB's protective function, selective permeability, and dynamic functionality …
Novel PLGA-based nanoformulation decreases doxorubicin-induced cardiotoxicity
N Drinković, M Beus, R Barbir, Ž Debeljak… - Nanoscale, 2024 - pubs.rsc.org
Nanotechnology has the potential to provide formulations of antitumor agents with increased
selectivity towards cancer tissue thereby decreasing systemic toxicity. This in vivo study …
selectivity towards cancer tissue thereby decreasing systemic toxicity. This in vivo study …
[HTML][HTML] PLGA nanoparticles for nasal drug delivery
The nasal route has routinely been used in the local delivery of drugs, however with
innovations in nanotechnology, there has been increased interest in exploring this route …
innovations in nanotechnology, there has been increased interest in exploring this route …
Internalization of PLGA nanoparticles coated with poloxamer 188 in glioma cells: a confocal laser scanning microscopy study
DV Beigulenko, AS Semyonkin… - Mendeleev …, 2023 - Elsevier
Internalization of poloxamer 188-coated PLGA nanoparticles (NPs) in GL261 murine glioma
cells was studied using confocal laser scanning microscopy. For visualization, both …
cells was studied using confocal laser scanning microscopy. For visualization, both …
Targeting the Blood-Brain Barrier with Nano-Biomaterials
SK Gowda, D Venkataramanamma… - … Inspired Nanomedicines for …, 2024 - Springer
The blood-brain barrier (BBB) is the most selective and dynamic boundary that controls the
exchange and transfer of molecules between blood circulation and the central nervous …
exchange and transfer of molecules between blood circulation and the central nervous …
Infection of human blood-brain barrier cells in vitro by different subtypes of enterovirus a71 and its consequences on permeability and particles release
IL Coqueiro - 2023 - theses.hal.science
The blood-brain barrier (BBB) formed by the brain microvasculature can be circumvented
during the invasion of the central nervous system (CNS) by neurotropic viruses. Enterovirus …
during the invasion of the central nervous system (CNS) by neurotropic viruses. Enterovirus …