microRNAs in action: biogenesis, function and regulation
Ever since microRNAs (miRNAs) were first recognized as an extensive gene family> 20
years ago, a broad community of researchers was drawn to investigate the universe of small …
years ago, a broad community of researchers was drawn to investigate the universe of small …
Life of RISC: Formation, action, and degradation of RNA-induced silencing complex
Small RNAs regulate a wide variety of biological processes by repressing the expression of
target genes at the transcriptional and post-transcriptional levels. To achieve these …
target genes at the transcriptional and post-transcriptional levels. To achieve these …
Regulation of microRNA biogenesis and its crosstalk with other cellular pathways
T Treiber, N Treiber, G Meister - Nature reviews Molecular cell biology, 2019 - nature.com
MicroRNAs (miRNAs) are short non-coding RNAs that inhibit the expression of target genes
by directly binding to their mRNAs. miRNAs are transcribed as precursor molecules, which …
by directly binding to their mRNAs. miRNAs are transcribed as precursor molecules, which …
[HTML][HTML] Metazoan micrornas
DP Bartel - Cell, 2018 - cell.com
MicroRNAs (miRNAs) are∼ 22 nt RNAs that direct posttranscriptional repression of mRNA
targets in diverse eukaryotic lineages. In humans and other mammals, these small RNAs …
targets in diverse eukaryotic lineages. In humans and other mammals, these small RNAs …
Small RNA-based antimicrobial immunity
Protection against microbial infection in eukaryotes is provided by diverse cellular and
molecular mechanisms. Here, we present a comparative view of the antiviral activity of virus …
molecular mechanisms. Here, we present a comparative view of the antiviral activity of virus …
MirGeneDB 2.0: the metazoan microRNA complement
Small non-coding RNAs have gained substantial attention due to their roles in animal
development and human disorders. Among them, microRNAs are special because …
development and human disorders. Among them, microRNAs are special because …
Argonaute proteins: from structure to function in development and pathological cell fate determination
M Müller, F Fazi, C Ciaudo - Frontiers in Cell and Developmental …, 2020 - frontiersin.org
The highly conserved Argonaute protein family members play a central role in the regulation
of gene expression networks, orchestrating the establishment and the maintenance of cell …
of gene expression networks, orchestrating the establishment and the maintenance of cell …
Mechanistic insights into microRNA-mediated gene silencing
TF Duchaine, MR Fabian - Cold Spring Harbor …, 2019 - cshperspectives.cshlp.org
MicroRNAs (miRNAs) posttranscriptionally regulate gene expression by repressing protein
synthesis and exert a broad influence over development, physiology, adaptation, and …
synthesis and exert a broad influence over development, physiology, adaptation, and …
Regulation and different functions of the animal microRNA‐induced silencing complex
PM Frédérick, MJ Simard - Wiley Interdisciplinary Reviews …, 2022 - Wiley Online Library
Among the different types of small RNAs, microRNAs (miRNAs) are key players in
controlling gene expression at the mRNA level. To be active, they must associate with an …
controlling gene expression at the mRNA level. To be active, they must associate with an …
Antiviral RNA interference in mammals
Highlights•Mammalian cells produce abundant viral siRNAs in response to distinct RNA
viruses.•Three mammalian viruses encode potent dsRNA-binding viral suppressors of …
viruses.•Three mammalian viruses encode potent dsRNA-binding viral suppressors of …