Novel biomedical applications of crosslinked collagen

L Gu, T Shan, Y Ma, FR Tay, L Niu - Trends in biotechnology, 2019 - cell.com
Collagen is one of the most useful biopolymers because of its low immunogenicity and
biocompatibility. The biomedical potential of natural collagen is limited by its poor …

TFOS Lifestyle: Impact of elective medications and procedures on the ocular surface

JAP Gomes, DT Azar, C Baudouin, E Bitton, W Chen… - The Ocular Surface, 2023 - Elsevier
The word “elective” refers to medications and procedures undertaken by choice or with a
lower grade of prioritization. Patients usually use elective medications or undergo elective …

Prevalence of keratoconus in paediatric patients in Riyadh, Saudi Arabia

EAT Netto, WM Al-Otaibi, NL Hafezi, S Kling… - British Journal of …, 2018 - bjo.bmj.com
Background/aim Keratoconus (KC) is a ectatic corneal disorder with marked progression
during childhood and puberty that may lead to severe visual loss. In addition to KC …

Progression of keratoconus and efficacy of corneal collagen cross-linking in children and adolescents

N Chatzis, F Hafezi - Journal of Refractive Surgery, 2012 - journals.healio.com
PURPOSE: To study the progression rate of keratoconus and assess the clinical outcome of
corneal collagen cross-linking (CXL) with riboflavin and ultraviolet A light in children and …

In vivo measurement of shear modulus of the human cornea using optical coherence elastography

A Ramier, AM Eltony, YT Chen, F Clouser… - Scientific reports, 2020 - nature.com
Corneal stiffness plays a critical role in shaping the cornea with respect to intraocular
pressure and physical interventions. However, it remains difficult to measure the mechanical …

Management of keratoconus: an updated review

R Deshmukh, ZZ Ong, R Rampat… - Frontiers in …, 2023 - frontiersin.org
Keratoconus is the most common corneal ectatic disorder. It is characterized by progressive
corneal thinning with resultant irregular astigmatism and myopia. Its prevalence has been …

Metabolomics and lipidomics approaches in human tears: A systematic review

RK Khanna, S Catanese, P Emond, P Corcia… - Survey of …, 2022 - Elsevier
The human tear film is at the interface between the ocular surface and the external
environment. Although investigation has been hindered by its small volume, improvements …

Ectasia risk factors in refractive surgery

MR Santhiago, NT Giacomin, D Smadja… - Clinical …, 2016 - Taylor & Francis
This review outlines risk factors of post-laser in situ keratomileusis (LASIK) ectasia that can
be detected preoperatively and presents a new metric to be considered in the detection of …

PACK-CXL vs. antimicrobial therapy for bacterial, fungal, and mixed infectious keratitis: a prospective randomized phase 3 trial

F Hafezi, M Hosny, R Shetty, B Knyazer, S Chen… - Eye and Vision, 2022 - Springer
Background Infectious keratitis is a major cause of global blindness. We tested whether
standalone photoactivated chromophore corneal cross-linking (PACK-CXL) may be an …

Collagen cross-linking: when and how? A review of the state of the art of the technique and new perspectives

L Mastropasqua - Eye and Vision, 2015 - Springer
Since the late 1990s corneal crosslinking (CXL) has been proposed as a new possibility to
stop progression of keratoconus or secondary corneal ectasia, with the promising aim to …