Glycomics studies using sialic acid derivatization and mass spectrometry
Proteins can undergo glycosylation during and/or after translation to afford glycoconjugates,
which are often secreted by a cell or populate cell surfaces. Changes in the glycan portion …
which are often secreted by a cell or populate cell surfaces. Changes in the glycan portion …
Glycan analysis by modern instrumental methods
M Pabst, F Altmann - Proteomics, 2011 - Wiley Online Library
The oligosaccharides attached to proteins or lipids are among the most challenging
analytical tasks due to their complexity and variety. Knowing the genes and enzymes …
analytical tasks due to their complexity and variety. Knowing the genes and enzymes …
Microfluidic capillary electrophoresis–mass spectrometry for analysis of monosaccharides, oligosaccharides, and glycopeptides
Glycomics and glycoproteomics analyses by mass spectrometry require efficient front-end
separation methods to enable deep characterization of heterogeneous glycoform …
separation methods to enable deep characterization of heterogeneous glycoform …
Glycan characterization of biopharmaceuticals: updates and perspectives
A Planinc, J Bones, B Dejaegher, P Van Antwerpen… - Analytica chimica …, 2016 - Elsevier
Therapeutic proteins are rapidly becoming the most promising class of pharmaceuticals on
the market due to their successful treatment of a vast array of serious diseases, such as …
the market due to their successful treatment of a vast array of serious diseases, such as …
In-depth structural analysis of glycans in the gas phase
E Mucha, A Stuckmann, M Marianski, WB Struwe… - Chemical …, 2019 - pubs.rsc.org
Although there have been substantial improvements in glycan analysis over the past
decade, the lack of both high-resolution and high-throughput methods hampers progress in …
decade, the lack of both high-resolution and high-throughput methods hampers progress in …
Sialic acid derivatization for glycan analysis by mass spectrometry
T Nishikaze - Proceedings of the Japan Academy, Series B, 2019 - jstage.jst.go.jp
Mass spectrometry (MS) is a well-accepted means for analyzing glycans. Before glycan
analysis by MS, several chemical derivatizations are generally carried out. These are …
analysis by MS, several chemical derivatizations are generally carried out. These are …
High-throughput analysis and automation for glycomics studies
This review covers advances in analytical technologies for high-throughput (HTP) glycomics.
Our focus is on structural studies of glycoprotein glycosylation to support biopharmaceutical …
Our focus is on structural studies of glycoprotein glycosylation to support biopharmaceutical …
Quantitative glycomics strategies
The correlations between protein glycosylation and many biological processes and
diseases are increasing the demand for quantitative glycomics strategies enabling sensitive …
diseases are increasing the demand for quantitative glycomics strategies enabling sensitive …
Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2009–2010
DJ Harvey - Mass spectrometry reviews, 2015 - Wiley Online Library
This review is the sixth update of the original article published in 1999 on the application of
MALDI mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings …
MALDI mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings …
Glycosylation biomarkers associated with age-related diseases and current methods for glycan analysis
Ageing is a complex process which implies the accumulation of molecular, cellular and
organ damage, leading to an increased vulnerability to disease. In Western societies, the …
organ damage, leading to an increased vulnerability to disease. In Western societies, the …