Exosomal circular RNAs: a chief culprit in cancer chemotherapy resistance

X Guo, C Gao, DH Yang, S Li - Drug Resistance Updates, 2023 - Elsevier
Chemotherapy is one of the primary treatments for malignant tumors. However, the acquired
drug resistance hinders clinical efficacy and leads to treatment failure in most patients …

Long noncoding RNAs in the pathogenesis of insulin resistance

W Yang, Y Lyu, R Xiang, J Yang - International journal of molecular …, 2022 - mdpi.com
Insulin resistance (IR), designated as the blunted response of insulin target tissues to
physiological level of insulin, plays crucial roles in the development and progression of …

The role of mesenchymal stem cells derived exosomes as a novel nanobiotechnology target in the diagnosis and treatment of cancer

Y Zhou, Y Dong, A Zhang, J Wu, Q Sun - Frontiers in Bioengineering …, 2023 - frontiersin.org
Mesenchymal stem cells (MSCs), one of the most common types of stem cells, are involved
in the modulation of the tumor microenvironment (TME). With the advancement of …

[HTML][HTML] Mesenchymal stem cell-derived exosomes as delivery vehicles for non-coding RNAs in lung diseases

Y Feng, K Guo, J Jiang, S Lin - Biomedicine & Pharmacotherapy, 2024 - Elsevier
The burden of lung diseases is gradually increasing with an increase in the average human
life expectancy. Therefore, it is necessary to identify effective methods to treat lung diseases …

Parkinson's disease: from genetics and epigenetics to treatment, a miRNA-based strategy

E Paccosi, L Proietti-De-Santis - International Journal of Molecular …, 2023 - mdpi.com
Parkinson's disease (PD) is one of the most common neurodegenerative disorders,
characterized by an initial and progressive loss of dopaminergic neurons of the substantia …

Mesenchymal stem cell-derived exosomes: versatile nanomaterials for skin wound treatment

Y Xiao, H Li, J Zhang, S Yang, C Zhang, Y Huang… - Nano Research, 2024 - Springer
Accumulating studies reveal that mesenchymal stem cells (MSCs) promote skin wound
healing mainly through the paracrine effects. Exosomes, one of the crucial paracrine …

Advances in purification, modification, and application of extracellular vesicles for novel clinical treatments

Y Matsuzaka, R Yashiro - Membranes, 2022 - mdpi.com
Extracellular vesicles (EV) are membrane vesicles surrounded by a lipid bilayer membrane
and include microvesicles, apoptotic bodies, exosomes, and exomeres. Exosome …

Mesenchymal Stem Cell-Derived Long Noncoding RNAs in Cardiac Injury and Repair

T Tran, C Cruz, A Chan, S Awad, J Rajasingh, R Deth… - Cells, 2023 - mdpi.com
Cardiac injury, such as myocardial infarction and heart failure, remains a significant global
health burden. The limited regenerative capacity of the adult heart poses a challenge for …

Emerging roles of mesenchymal stem/stromal-cell-derived extracellular vesicles in cancer therapy

A Nicodemou, S Bernátová, M Čeháková, Ľ Danišovič - Pharmaceutics, 2023 - mdpi.com
Despite the tremendous efforts of many researchers and clinicians, cancer remains the
second leading cause of mortality worldwide. Mesenchymal stem/stromal cells (MSCs) are …

Therapeutic potential of extracellular vesicles from diverse sources in cancer treatment

H Lin, J Zhou, T Ding, Y Zhu, L Wang, T Zhong… - European Journal of …, 2024 - Springer
Cancer, a prevalent and complex disease, presents a significant challenge to the medical
community. It is characterized by irregular cell differentiation, excessive proliferation …