Light pollution, circadian photoreception, and melatonin in vertebrates
Artificial light at night (ALAN) is increasing exponentially worldwide, accelerated by the
transition to new efficient lighting technologies. However, ALAN and resulting light pollution …
transition to new efficient lighting technologies. However, ALAN and resulting light pollution …
Individual differences in light sensitivity affect sleep and circadian rhythms
SL Chellappa - Sleep, 2021 - academic.oup.com
Artificial lighting is omnipresent in contemporary society with disruptive consequences for
human sleep and circadian rhythms because of overexposure to light, particularly in the …
human sleep and circadian rhythms because of overexposure to light, particularly in the …
High sensitivity and interindividual variability in the response of the human circadian system to evening light
Before the invention of electric lighting, humans were primarily exposed to intense (> 300
lux) or dim (< 30 lux) environmental light—stimuli at extreme ends of the circadian system's …
lux) or dim (< 30 lux) environmental light—stimuli at extreme ends of the circadian system's …
The role of daylight for humans: gaps in current knowledge
Daylight stems solely from direct, scattered and reflected sunlight, and undergoes dynamic
changes in irradiance and spectral power composition due to latitude, time of day, time of …
changes in irradiance and spectral power composition due to latitude, time of day, time of …
The photobiology of the human circadian clock
RA Schoonderwoerd, M de Rover… - Proceedings of the …, 2022 - National Acad Sciences
In modern society, the widespread use of artificial light at night disrupts the suprachiasmatic
nucleus (SCN), which serves as our central circadian clock. Existing models describe …
nucleus (SCN), which serves as our central circadian clock. Existing models describe …
Neurogenetic basis for circadian regulation of metabolism by the hypothalamus
Circadian rhythms are driven by a transcription–translation feedback loop that separates
anabolic and catabolic processes across the Earth's 24-h light–dark cycle. Central …
anabolic and catabolic processes across the Earth's 24-h light–dark cycle. Central …
Factors associated with variability in the melatonin suppression response to light: A narrative review
Light is the main environmental signal synchronizing circadian rhythms to the 24-hour light-
dark cycle. Recent research has identified significant inter-individual variability in the …
dark cycle. Recent research has identified significant inter-individual variability in the …
Naturalistic intensities of light at night: A review of the potent effects of very dim light on circadian responses and considerations for translational research
TJ Walbeek, EM Harrison, MR Gorman… - Frontiers in …, 2021 - frontiersin.org
In this review, we discuss the remarkable potency and potential applications of a form of light
that is often overlooked in a circadian context: naturalistic levels of dim light at night (nLAN) …
that is often overlooked in a circadian context: naturalistic levels of dim light at night (nLAN) …
Direct effects of the light environment on daily neuroendocrine control
S Paul, TM Brown - Journal of Endocrinology, 2019 - joe.bioscientifica.com
Endocrine systems function as key mediators of adaptive responses to the external
environment. As a reliable predictor of many salient variations in the external world, the light …
environment. As a reliable predictor of many salient variations in the external world, the light …
Afraid of the dark: Light acutely suppresses activity in the human amygdala
Light improves mood. The amygdala plays a critical role in regulating emotion, including fear-
related responses. In rodents the amygdala receives direct light input from the retina, and …
related responses. In rodents the amygdala receives direct light input from the retina, and …