Stress plays a key role in pathogenesis of anxiety and depression. Animal models of these
disorders are widely used in behavioral neuroscience to explore stress-evoked brain …

Animals occupy territories in which resources such as food and shelter are often distributed
unevenly. While studies of exploratory behavior have typically involved the laboratory rodent …

Serotonin transporter knockout (SERT−/−) mice are extensively used as a genetic model of
several neuropsychiatric disorders, and consistently display anxiety-like behaviors and …

Widely used behavioral assays need re-evaluation and validation against their intended
use. We focus here on measures of chronic anxiety in mouse models and posit that widely …

The demand for replicability of behavioral results across laboratories is viewed as a burden
in behavior genetics. We demonstrate how it can become an asset offering a quantitative …

Animal models of human diseases of the central nervous system, generalized anxiety
disorder included, are essential for the study of the brain-behavior interface and obligatory …

Spatial memory is often studied in the Morris Water Maze, where the animal's spatial
orientation has been shown to be mainly shaped by distal visual cues. Cognition-related …

The physicality of the world in which the animal acts—its anatomical structure, physiology,
perception, emotional states, and cognitive capabilities—determines the boundaries of the …

The tree of life is decorated with an extraordinary diversity of animal behavior (figure 11.1).
Such behaviors as foraging, reproducing, moving through the environment, and avoiding …

Abstract Background Polychlorinated biphenyls (PCBs) are widespread in the environment,
human food and breast milk. Seafood is known to contain nutrients beneficial for the normal …