What's wrong with my mouse model?: Advances and strategies in animal modeling of anxiety and depression
AV Kalueff, M Wheaton, DL Murphy - Behavioural brain research, 2007 - Elsevier
Stress plays a key role in pathogenesis of anxiety and depression. Animal models of these
disorders are widely used in behavioral neuroscience to explore stress-evoked brain …
disorders are widely used in behavioral neuroscience to explore stress-evoked brain …
Behavioral and neural subsystems of rodent exploration
Animals occupy territories in which resources such as food and shelter are often distributed
unevenly. While studies of exploratory behavior have typically involved the laboratory rodent …
unevenly. While studies of exploratory behavior have typically involved the laboratory rodent …
Locomotory patterns, spatiotemporal organization of exploration and spatial memory in serotonin transporter knockout mice
AV Kalueff, CL Jensen, DL Murphy - Brain research, 2007 - Elsevier
Serotonin transporter knockout (SERT−/−) mice are extensively used as a genetic model of
several neuropsychiatric disorders, and consistently display anxiety-like behaviors and …
several neuropsychiatric disorders, and consistently display anxiety-like behaviors and …
Measuring behavior of animal models: faults and remedies
Widely used behavioral assays need re-evaluation and validation against their intended
use. We focus here on measures of chronic anxiety in mouse models and posit that widely …
use. We focus here on measures of chronic anxiety in mouse models and posit that widely …
Ten ways to improve the quality of descriptions of whole-animal movement
The demand for replicability of behavioral results across laboratories is viewed as a burden
in behavior genetics. We demonstrate how it can become an asset offering a quantitative …
in behavior genetics. We demonstrate how it can become an asset offering a quantitative …
Short and long term measures of anxiety exhibit opposite results
Animal models of human diseases of the central nervous system, generalized anxiety
disorder included, are essential for the study of the brain-behavior interface and obligatory …
disorder included, are essential for the study of the brain-behavior interface and obligatory …
Mouse cognition-related behavior in the open-field: emergence of places of attraction
A Dvorkin, Y Benjamini, I Golani - PLoS computational biology, 2008 - journals.plos.org
Spatial memory is often studied in the Morris Water Maze, where the animal's spatial
orientation has been shown to be mainly shaped by distal visual cues. Cognition-related …
orientation has been shown to be mainly shaped by distal visual cues. Cognition-related …
High mirror symmetry in mouse exploratory behavior
E Fonio, O Feinerman - Frontiers in Behavioral Neuroscience, 2024 - frontiersin.org
The physicality of the world in which the animal acts—its anatomical structure, physiology,
perception, emotional states, and cognitive capabilities—determines the boundaries of the …
perception, emotional states, and cognitive capabilities—determines the boundaries of the …
[PDF][PDF] Behavior and neurobiology
JS Rhodes, TJ Kawecki - Experimental evolution: concepts …, 2009 - researchgate.net
The tree of life is decorated with an extraordinary diversity of animal behavior (figure 11.1).
Such behaviors as foraging, reproducing, moving through the environment, and avoiding …
Such behaviors as foraging, reproducing, moving through the environment, and avoiding …
Long-term effects of environmentally relevant doses of 2, 2', 4, 4', 5, 5'hexachlorobiphenyl (PCB153) on neurobehavioural development, health and spontaneous …
M Haave, A Bernhard, FK Jellestad… - Behavioral and Brain …, 2011 - Springer
Abstract Background Polychlorinated biphenyls (PCBs) are widespread in the environment,
human food and breast milk. Seafood is known to contain nutrients beneficial for the normal …
human food and breast milk. Seafood is known to contain nutrients beneficial for the normal …