Sertoli cell as a model in male reproductive toxicology: Advantages and disadvantages

MMS Reis, AC Moreira, M Sousa… - Journal of Applied …, 2015 - Wiley Online Library
Pressure towards population aging in the demographic pyramid is not only due to
sociological/personal choices but also due to subfertility or infertility. There are several …

Effects of dietary vitamin E on male reproductive system

M Zubair - Asian Pacific Journal of Reproduction, 2017 - journals.lww.com
Vitamin E is known as important antioxidant to protect the reproductive system. The free
radicals are continuously produced in last few years due to metabolic and nutritional …

Smart Hesperidin/Chitosan Nanogel Mitigates Apoptosis and Endoplasmic Reticulum Stress in Fluoride and Aluminum-Induced Testicular Injury

NS Deiab, AS Kodous, MK Mahfouz, AM Said… - … Trace Element Research, 2024 - Springer
Fluoride and aluminum are ubiquitous toxic metals with adverse reproductive effects. The
citrus flavonoid hesperidin has protective activities but poor solubility and bioavailability …

Ameliorative effect of vitamins (α-tocopherol and ascorbic acid) on PCB (Aroclor 1254) induced oxidative stress in rat epididymal sperm

G Krishnamoorthy, P Venkataraman, A Arunkumar… - Reproductive …, 2007 - Elsevier
The aim of this study was to investigate the possible protective role of vitamins on PCB
(Aroclor 1254)-induced spermiotoxicity using qualitative, quantitative and biochemical …

Aroclor1254 disrupts the blood–testis barrier by promoting endocytosis and degradation of junction proteins via p38 MAPK pathway

X Jia, Y Xu, W Wu, Y Fan, G Wang, T Zhang… - Cell Death & …, 2017 - nature.com
The blood–testis barrier (BTB) constituted by coexisting junction apparatus between Sertoli
cells (SCs) plays an important role in spermatogenesis, which is a known target of various …

Aroclor 1254 impairs spermatogenesis and induces oxidative stress in rat testicular mitochondria

HAA Aly, Ò Domènech, AB Abdel-Naim - Food and chemical toxicology, 2009 - Elsevier
Aroclor 1254 (A1254) has been shown to have potential testicular toxicity. The mechanism
of action of A1254 on male reproduction is not clear. The present study was designed to …

Antioxidant effect of ascorbic acid on PCB (Aroclor 1254) induced oxidative stress in hypothalamus of albino rats

R Muthuvel, P Venkataraman, G Krishnamoorthy… - Clinica Chimica …, 2006 - Elsevier
BACKGROUND: PCBs are one of the environmental toxicants and neurotoxic compounds
which induce the production of free radicals leading to oxidative stress. Vitamin C is well …

Effect of quercetin on haematobiochemical and histological changes in the liver of polychlorined biphenyls‐induced adult male Wistar rats

K Selvakumar, S Bavithra, S Suganya… - Journal of …, 2013 - Wiley Online Library
Polychlorinated biphenyls exposure damages the rat liver cells. Hematological parameters
such as hemoglobin, packed cell volume, red‐blood cells, white‐blood cells, neutrophils …

Intracellular toxicity exerted by PCBs and role of VBNC bacterial strains in biodegradation

K Murugan, N Vasudevan - Ecotoxicology and environmental safety, 2018 - Elsevier
Polychlorinated biphenyls (PCBs) are xenobiotic compounds that persists in the
environment for long-term, though its productivity is banned. Abatement of the pollutants …

PCB (Aroclor 1254) enhances oxidative damage in rat brain regions: protective role of ascorbic acid

P Venkataraman, R Muthuvel, G Krishnamoorthy… - Neurotoxicology, 2007 - Elsevier
PCBs are one of the environmental toxicants and neurotoxic compounds which induce the
production of free radicals leading to oxidative stress. Oxidative stress is a contributing factor …