Inflammation plays an important role in the response to danger signals arising from damage
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …

Navigation through the bulk tumour, entry into the blood vasculature, survival in the
circulation, exit at distant sites and resumption of proliferation are all steps necessary for …

A therapeutic strategy that targets multiple proinflammatory factors in inflammatory bowel
disease (IBD) with minimal systemic side effects would be attractive. Here, we develop a …

Periodontitis is a common type of inflammatory bone loss and a risk factor for systemic
diseases. The pathogenesis of periodontitis involves inflammatory dysregulation, which …

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy. PDAC is only
cured by surgical resection in its early stage, but there remains a relatively high possibility of …

Severe sepsis represents a common, expensive, and deadly health care issue with limited
therapeutic options. Gaining insights into the inflammatory dysregulation that causes sepsis …

Millions of COVID-19 patients have succumbed to respiratory and systemic inflammation.
Hyperstimulation of toll-like receptor (TLR) signaling is a key driver of immunopathology …

Photothermal therapy (PTT) is an effective treatment modality that is highly selective for
tumor suppression and is a hopeful alternative to traditional cancer therapy. However, PTT …

Irreversible electroporation (IRE) is a nonthermal ablation technique that is used clinically in
selected patients with locally advanced pancreatic cancer, but most patients develop …

Abstract Design of micro-or nanocarriers for drug delivery has primarily been focused on
properties such as hydrophobicity, biodegradability, size, shape, surface charge, and …