The Use of Poly(N-vinyl pyrrolidone) in the Delivery of Drugs: A Review
P Franco, I De Marco - Polymers, 2020 - mdpi.com
Polyvinylpyrrolidone (PVP) is a hydrophilic polymer widely employed as a carrier in the
pharmaceutical, biomedical, and nutraceutical fields. Up to now, several PVP-based …
pharmaceutical, biomedical, and nutraceutical fields. Up to now, several PVP-based …
Overview of the manufacturing methods of solid dispersion technology for improving the solubility of poorly water-soluble drugs and application to anticancer drugs
P Tran, YC Pyo, DH Kim, SE Lee, JK Kim, JS Park - Pharmaceutics, 2019 - mdpi.com
Approximately 40% of new chemical entities (NCEs), including anticancer drugs, have been
reported as poorly water-soluble compounds. Anticancer drugs are classified into biologic …
reported as poorly water-soluble compounds. Anticancer drugs are classified into biologic …
Polymeric amorphous solid dispersions: a review of amorphization, crystallization, stabilization, solid-state characterization, and aqueous solubilization of …
S Baghel, H Cathcart, NJ O'Reilly - Journal of pharmaceutical sciences, 2016 - Elsevier
Poor water solubility of many drugs has emerged as one of the major challenges in the
pharmaceutical world. Polymer-based amorphous solid dispersions have been considered …
pharmaceutical world. Polymer-based amorphous solid dispersions have been considered …
Spray drying of pharmaceuticals and biopharmaceuticals: Critical parameters and experimental process optimization approaches
Spray drying is increasingly becoming recognized as an efficient drying and formulation
technique for pharmaceutical and biopharmaceutical processing. It offers significant …
technique for pharmaceutical and biopharmaceutical processing. It offers significant …
Spray drying formulation of amorphous solid dispersions
A Singh, G Van den Mooter - Advanced drug delivery reviews, 2016 - Elsevier
Spray drying is a well-established manufacturing technique which can be used to formulate
amorphous solid dispersions (ASDs) which is an effective strategy to deliver poorly water …
amorphous solid dispersions (ASDs) which is an effective strategy to deliver poorly water …
[HTML][HTML] Dry powder for pulmonary delivery: A comprehensive review
B Chaurasiya, YY Zhao - Pharmaceutics, 2021 - mdpi.com
The pulmonary route has long been used for drug administration for both local and systemic
treatment. It possesses several advantages, which can be categorized into physiological, ie …
treatment. It possesses several advantages, which can be categorized into physiological, ie …
Manufacturing of solid dispersions of poorly water soluble drugs by spray drying: formulation and process considerations
Spray drying is an efficient technology for solid dispersion manufacturing since it allows
extreme rapid solvent evaporation leading to fast transformation of an API-carrier solution to …
extreme rapid solvent evaporation leading to fast transformation of an API-carrier solution to …
The use of amorphous solid dispersions: A formulation strategy to overcome poor solubility and dissolution rate
G Van den Mooter - Drug Discovery Today: Technologies, 2012 - Elsevier
The use of amorphous solid dispersions is an interesting strategy to increase the
bioavailability of poorly soluble drugs by improving their rate and extent of dissolution. Lack …
bioavailability of poorly soluble drugs by improving their rate and extent of dissolution. Lack …
Recent strategies in spray drying for the enhanced bioavailability of poorly water-soluble drugs
Poorly water-soluble drugs are a significant and ongoing issue for the pharmaceutical
industry. An overview of recent developments for the preparation of spray-dried delivery …
industry. An overview of recent developments for the preparation of spray-dried delivery …
Engineering advances in spray drying for pharmaceuticals
JM Baumann, MS Adam, JD Wood - Annual review of chemical …, 2021 - annualreviews.org
Spray drying is a versatile technology that has been applied widely in the chemical, food,
and, most recently, pharmaceutical industries. This review focuses on engineering advances …
and, most recently, pharmaceutical industries. This review focuses on engineering advances …