Thyroid nodule molecular testing: is it ready for prime time?

TM Khan, MA Zeiger - Frontiers in Endocrinology, 2020 - frontiersin.org
Cytologically indeterminate thyroid nodules remain a diagnostic and clinical challenge, and
molecular testing has been advocated and advanced as a diagnostic modality to help guide …

Molecular characterization of thyroid follicular lesions in the era of “next-generation” techniques

ED Rossi, P Locantore, C Bruno… - Frontiers in …, 2022 - frontiersin.org
It is unequivocally recognized that thyroid nodules are frequently detected in the adult
population and mostly characterized by benign lesions (up to 70% of them), with only 5 …

The molecular landscape of Hürthle cell thyroid cancer is associated with altered mitochondrial function—a comprehensive review

S Kumari, R Adewale, J Klubo-Gwiezdzinska - Cells, 2020 - mdpi.com
Hürthle cell thyroid carcinoma (HTC) accounts for 3–5% of all thyroid malignancies. Widely
invasive HTC is characterized by poor prognosis and limited responsiveness to standard …

Challenges in cytology specimens with Hürthle cells

E Thodou, S Canberk, F Schmitt - Frontiers in Endocrinology, 2021 - frontiersin.org
In fine-needle aspirations (FNA) of thyroid, Hürthle cells can be found in a broad spectrum of
lesions, ranging from non-neoplastic conditions to aggressive malignant tumors. Recognize …

A retrospective study of clinicopathologic outcomes of nodules with hürthle cell cytology and the thyroid nodule app (TNAPP) ultrasound recommendations

GM Spagnuolo, HT Tierney, NMV Laver, LS Eldeiry - Endocrine Practice, 2022 - Elsevier
Objectives Hürthle cells are a common finding on thyroid fine-needle aspiration, but when
they are the predominant cytology, they represent a difficult diagnostic challenge. The …

Development and validation of molecular assays for limited tissue samples

R Sussman, JN Rosenbaum - Acta Cytologica, 2020 - karger.com
As the value of molecular testing of cancer specimens increases, the number of tests
imposed on tumor specimens also increases, often in tension with the amount of tumor …

EIF1AX c. 338-2A> T splice site mutation in a patient with trabecular adenoma and cytological indeterminate lesion

MG Castagna, T Pilli, F Maino, C Marzocchi… - … of Endocrinology and …, 2020 - SciELO Brasil
The EIF1AX gene mutations have been recently associated with papillary thyroid carcinoma
and anaplastic thyroid cancer. According with these reports, the gene as been considered …

Fine-needle aspiration and molecular analysis

BJ Gigliotti, MD Russell, D Shonka… - Surgery of the Thyroid and …, 2021 - Elsevier
Indeterminate cytopathology has been a major clinical challenge in the identification of
malignancy in thyroid nodules by fine-needle aspiration. Diagnostic lobectomy has long …

[图书][B] Recent Advances and Researches in the Field of Fine Needle Aspiration Cytopathology

A Goyal - 2023 - intechopen.com
Fine needle aspiration cytology/biopsy (FNAB) is quite often one of the first tests for the initial
evaluation of lesions/swellings which are accessible to the needle tracts. The technique has …

Follicular Neoplasm Hürthle Cell (Oncocytic) Type/Suspicious for Follicular Neoplasm Hürthle Cell (Oncocytic) Type

RS Hoda, R Rao, T Scognamiglio - Atlas of Thyroid Cytopathology on …, 2020 - Springer
Follicular Neoplasm Hürthle Cell (Oncocytic) Type/Suspicious for Follicular Neoplasm Hürthle
Cell (Oncocytic) Type | SpringerLink Skip to main content Advertisement SpringerLink Account …