Gold nanoparticles in nanobiotechnology: From synthesis to biosensing applications

A Karnwal, RS Kumar Sachan, I Devgon, J Devgon… - ACS …, 2024 - ACS Publications
Nanobiotechnology has ushered in a new era of scientific discovery where the unique
properties of nanomaterials, such as gold nanoparticles, have been harnessed for a wide …

Schematic-portfolio of potent anti-microbial scaffolds targeting DNA gyrase: unlocking ways to overcome resistance

K Pakeeraiah, S Mal, M Mahapatra, SK Mekap… - International Journal of …, 2024 - Elsevier
Drug development process demands validation of specific drug target impeding the Multi
Drug Resistance (MDR). DNA gyrase, as a bacterial target has been in trend for developing …

The impact of diabetes mellitus on the emergence of multi-drug resistant tuberculosis and treatment failure in TB-diabetes comorbid patients: a systematic review and …

A Rehman, M Khattak, U Mushtaq, M Latif… - Frontiers in Public …, 2023 - frontiersin.org
Background The existence of Type 2 Diabetes Mellitus (DM) in tuberculosis (TB) patients is
very dangerous for the health of patients. One of the major concerns is the emergence of …

[HTML][HTML] The Many Lives of Auranofin: How an Old Anti-Rheumatic Agent May Become a Promising Antimicrobial Drug

F Coscione, S Zineddu, V Vitali, M Fondi, L Messori… - Antibiotics, 2024 - mdpi.com
Auranofin (AF) is a gold-based compound with a well-known pharmacological and
toxicological profile, currently used in the treatment of some severe forms of rheumatoid …

Decoding drug resistance in Mycobacterium tuberculosis complex: genetic insights and future challenges

A Deshpande, R Likhar, T Khan… - Expert Review of Anti …, 2024 - Taylor & Francis
Introduction Tuberculosis (TB), particularly its drug-resistant forms (MDR-TB and XDR-TB),
continues to pose a significant global health challenge. Despite advances in treatment and …

Novel strategies based on natural products and synthetic derivatives to overcome resistance in Mycobacterium tuberculosis

AG Niculescu, GR Mük, S Avram, IM Vlad… - European Journal of …, 2024 - Elsevier
One of the biggest health challenges of today's world is the emergence of antimicrobial
resistance (AMR), which renders conventional therapeutics insufficient and urgently …

Development of a self-microemulsifying drug delivery system to deliver delamanid via a pressurized metered dose inhaler for treatment of multi-drug resistant …

H Paliwal, T Nakpheng, PK Paul, KP Ananth… - International Journal of …, 2024 - Elsevier
Tuberculosis (TB) is a serious health issue that contributes to millions of deaths throughout
the world and increases the threat of serious pulmonary infections in patients with …

Computational insights into potential marine natural products as selective inhibitors of Mycobacterium tuberculosis InhA: A structure-based virtual screening study

M Jayaraman, V Gosu, R Kumar… - Computational Biology and …, 2024 - Elsevier
Several factors are associated with the emergence of drug resistance mechanisms, such as
impermeable cell walls, gene mutations, and drug efflux systems. Consequently, bacteria …

Prediction of structure of mycobacterial efflux pump protein Rv0194 and molecular dynamics simulation of the predicted structures

SS Biswas, JD Roy - Biocatalysis and Agricultural Biotechnology, 2024 - Elsevier
Tuberculosis is a major cause of morbidity and mortality primarily in developing nations. The
rising number of cases of multidrug resistance and extensive drug resistance are a critical …

The Impact of Dogs Oral Microbiota on Human Health: A review

ALA Hadba, R Aburokba, A Alotiby… - Biosciences …, 2024 - biotech-asia.org
The dog's mouth contains many bacteria, with more than 600 types present. Therefore, it's
clear that dog saliva is not inherently cleaner than human saliva. Bacterial infections …