[HTML][HTML] Advances in the evolutionary understanding of MHC polymorphism

J Radwan, W Babik, J Kaufman, TL Lenz, J Winternitz - Trends in Genetics, 2020 - cell.com
Proteins encoded by the classical major histocompatibility complex (MHC) genes incite the
vertebrate adaptive immune response by presenting peptide antigens on the cell surface …

The inflated significance of neutral genetic diversity in conservation genetics

JC Teixeira, CD Huber - Proceedings of the National …, 2021 - National Acad Sciences
The current rate of species extinction is rapidly approaching unprecedented highs, and life
on Earth presently faces a sixth mass extinction event driven by anthropogenic activity …

Avian MHC evolution in the era of genomics: phase 1.0

EA O'Connor, H Westerdahl, R Burri, SV Edwards - Cells, 2019 - mdpi.com
Birds are a wonderfully diverse and accessible clade with an exceptional range of ecologies
and behaviors, making the study of the avian major histocompatibility complex (MHC) of …

Immunogenetic variation shapes the gut microbiome in a natural vertebrate population

CS Davies, SF Worsley, KH Maher, J Komdeur, T Burke… - Microbiome, 2022 - Springer
Background The gut microbiome (GM) can influence many biological processes in the host,
impacting its health and survival, but the GM can also be influenced by the host's traits. In …

Major histocompatibility complex class I diversity limits the repertoire of T cell receptors

M Migalska, A Sebastian… - Proceedings of the …, 2019 - National Acad Sciences
Major histocompatibility complex (MHC) genes encode proteins that initiate adaptive
immune responses through the presentation of foreign antigens to T cells. The high …

Evidence of MHC class I and II influencing viral and helminth infection via the microbiome in a non-human primate

BK Montero, Wasimuddin, N Schwensow… - PLoS …, 2021 - journals.plos.org
Until recently, the study of major histocompability complex (MHC) mediated immunity has
focused on the direct link between MHC diversity and susceptibility to parasite infection …

Evolution of major histocompatibility complex gene copy number

P Bentkowski, J Radwan - PLOS Computational Biology, 2019 - journals.plos.org
MHC genes, which code for proteins responsible for presenting pathogen-derived antigens
to the host immune system, show remarkable copy-number variation both between and …

[图书][B] Parasitology: a conceptual approach

ES Loker, BV Hofkin - 2022 - taylorfrancis.com
Produced amidst the still rippling effects of a pandemic and as the world experiences the
increasing burden of global warming and a rapidly changing biosphere, the second edition …

Long term patterns of association between MHC and helminth burdens in the bank vole support Red Queen dynamics

M Migalska, K Przesmycka, M Alsarraf… - Molecular …, 2022 - Wiley Online Library
Major histocompatibility complex (MHC) genes encode proteins crucial for adaptive
immunity of vertebrates. Negative frequency‐dependent selection (NFDS), resulting from …

The avian major histocompatibility complex

J Kaufman - Avian Immunology, 2022 - Elsevier
The major histocompatibility complex (MHC) is a genetic region encoding classical class I
and class II molecules that are highly polymorphic, are widely and strongly expressed …