Genetic variation in DNA repair genes can modulate DNA repair capacity and may be
related to cancer risk. However, study findings have been inconsistent. Inheritance of variant …

To evaluate the contribution of candidate gene association studies to the understanding of
genetic susceptibility to childhood acute lymphoblastic leukemia we conducted a systematic …

Acute leukaemias (AL) correspond to 25–35% of all cancer cases in children. The aetiology
is still sheltered, although several factors are implicated in causality of AL subtypes …

Although childhood acute lymphoblastic leukemia is the most common pediatric cancer, its
etiology remains poorly understood. In an attempt to replicate the findings of 2 recent …

Single nucleotide polymorphisms (SNPs) are the most frequent type of genetic alterations
between individuals. An SNP located within the coding sequence of a gene may lead to an …

The genetic polymorphisms of X‐ray repair cross complementing group 1 (XRCC1), X‐ray
repair cross complementing group 3 (XRCC3), and xeroderma pigmentosum …

There are a paucity and contradicted data about the impact of concurrent heredity of
polymorphic genes and risk of chronic myeloid leukemia (CML). In the present study, the …

DNA repair pathways, which are also identified as guardians of the genome, protect cells
from frequent damage that can lead to DNA breaks. The most deleterious types of damage …

Acute lymphoblastic leukemia (ALL) is a malignant tumor common in children. Studies of
genetic susceptibility to cancer using biallelic insertion/deletion (INDEL) type polymorphisms …

The aim of this study was to evaluate the association of polymorphisms in genes encoding
three key proteins of DNA base excision repair (BER): the OGG1 Ser326Cys, the MUTYH …