Observational findings achieved during the past two decades suggest that the intestinal
microbiota may contribute to the metabolic health of the human host and, when aberrant, to …

Obesity is a complex condition that interweaves biological, developmental, environmental,
behavioral, and genetic factors; it is a significant public health problem. The most common …

Bariatric surgery has been proved to be effective and sustainable in the long-term weight-
loss and remission of metabolic disorders. However, the underlying mechanisms are still far …

Metabolomics emerged as an important tool to gain insights on how the body responds to
therapeutic interventions. Bariatric surgery is the most effective treatment for severe obesity …

Background Chronic inflammation in adipose tissue may play a substantial role in the
pathogenesis of obesity‐related metabolic disorders. The present study aims to evaluate the …

Obesity is a grave concern within the United States, resulting in lost productivity, increased
medical costs, and comorbidities with lifelong repercussions. The laparoscopic sleeve …

A systematic review and meta‐analysis was conducted of studies that address the
association of bile acid (BA) with obesity and of studies on the effects of treatment in patients …

Abstract Knowledge about in vivo effects of human circulating C-6 hydroxylated bile acids
(BAs), also called muricholic acids, is sparse. It is unsettled if the gut microbiome might …

The adipokine CTRP-3 (C1q/TNF-related protein-3) exerts anti-inflammatory and anti-
diabetic effects. Its regulation in obesity and during weight loss is unknown. Serum and …

Vertical sleeve gastrectomy (VSG) is the best current therapy for remission of obesity and its
comorbidities. It is understood to alter the enterohepatic circulation of bile acids in vivo …