Abstract The programmability of Watson–Crick base pairing, combined with a decrease in
the cost of synthesis, has made DNA a widely used material for the assembly of molecular …

The specificity and predictability of Watson–Crick base pairing make DNA a powerful and
versatile material for engineering at the nanoscale. This has enabled the construction of a …

DNA is increasingly being used as the engineering material of choice for the construction of
nanoscale circuits, structures, and motors. Many of these enzyme-free constructions function …

In nature, self-assembling and disassembling complexes of proteins and nucleic acids
bound to a variety of ligands perform intricate and diverse dynamic functions. In contrast …

Artificial biochemical circuits are likely to play as large a role in biological engineering as
electrical circuits have played in the engineering of electromechanical devices. Toward that …

We explore in detail the structural, mechanical, and thermodynamic properties of a coarse-
grained model of DNA similar to that recently introduced in a study of DNA nanotweezers …

We are learning to build synthetic molecular machinery from DNA. This research is inspired
by biological systems in which individual molecules act, singly and in concert, as specialized …

A substantial challenge in engineering molecular motors is designing mechanisms to
coordinate the motion between multiple domains of the motor so as to bias random thermal …

originally designed to reproduce the properties of DNA molecules with average sequences.
The new parametrization introduces sequence-dependent stacking and base-pairing …

Controlled motion at the nanoscale can be achieved by using Watson–Crick base-pairing to
direct the assembly and operation of a molecular transport system consisting of a track, a …