Biological molecules such as DNA, proteins, and lipids can be assembled into naturally
existing nanoparticles, such as bacterial viruses (also called bacteriophages or phages) …

RNA interference (RNAi) is a remarkable endogenous regulatory pathway that can bring
about sequence-specific gene silencing. If harnessed effectively, RNAi could result in a …

Phagosome maturation is the process by which internalized particles (such as bacteria and
apoptotic cells) are trafficked into a series of increasingly acidified membrane-bound …

Background RNA interference (RNAi) is a highly conserved cellular mechanism. In some
organisms, such as Caenorhabditis elegans, the RNAi response can be transmitted …

Caspase activation has been frequently viewed as synonymous with apoptotic cell death;
however, caspases can also contribute to processes that do not culminate in cell demise …

Apoptosis-inducing factor (AIF) is a mitochondrial flavoprotein that, beyond its apoptotic
function, is required for the normal expression of major respiratory chain complexes. Here …

RNA engineering for nanotechnology and medical applications is an exciting emerging
research field. RNA has intrinsically defined features on the nanometre scale and is a …

Two classes of nucleases degrade the cellular DNA during apoptosis. Cell-autonomous
nucleases cleave DNA within the dying cell. They are not essential for apoptotic cell death or …

Apoptosis, an evolutionarily conserved programme of cellular self-destruction, is essential
for the development and survival of most multicellular animals. It is required to ensure …

Removal of apoptotic cells is critical for the physiological well-being of the organism and
defects in corpse removal have been linked to disease states,. Genes regulating corpse …