Baricitinib for the treatment of alopecia areata

E Freitas, E Guttman-Yassky, T Torres - Drugs, 2023 - Springer
Alopecia areata (AA) is a relapsing, chronic, immune-mediated disease characterized by
nonscarring, inflammatory hair loss that can affect any hair-bearing site. AA clinical …

Psychological stress-induced pathogenesis of alopecia areata: autoimmune and apoptotic pathways

D Ahn, H Kim, B Lee, DH Hahm - International Journal of Molecular …, 2023 - mdpi.com
Alopecia areata (AA) is an autoimmune dermatological disease with multifactorial etiology
and is characterized by reversible hair loss in patches. AA may be closely related to …

JAK-STAT pathway inhibitors in dermatology

HA Miot, PR Criado, CCS Castro, M Ianhez… - Anais brasileiros de …, 2023 - SciELO Brasil
The JAK-STAT signaling pathway mediates important cellular processes such as immune
response, carcinogenesis, cell differentiation, division and death. Therefore, drugs that …

Clinical and genetic aspects of alopecia areata: a cutting edge review

CY Ho, CY Wu, JYF Chen, CY Wu - Genes, 2023 - mdpi.com
Alopecia areata (AA) is a chronic, non-scarring, immune-mediated skin disease that affects
approximately 0.5–2% of the global population. The etiology of AA is complex and involves …

Systematic review of mesotherapy: a novel avenue for the treatment of hair loss

AK Gupta, S Polla Ravi, T Wang… - Journal of …, 2023 - Taylor & Francis
Mesotherapy is a technique by which lower doses of therapeutic agents and bioactive
substances are administered by intradermal injections to the skin. Through intradermal …

Inflammatory loops in the epithelial–immune microenvironment of the skin and skin appendages in chronic inflammatory diseases

T Dainichi, M Iwata - Frontiers in Immunology, 2023 - frontiersin.org
The epithelial–immune microenvironment (EIME) of epithelial tissues has five common
elements:(1) microbial flora,(2) barrier,(3) epithelial cells,(4) immune cells, and (5) …

Comparative efficacy of oral Janus kinase inhibitors and biologics in adult alopecia areata: A systematic review and Bayesian network meta‐analysis

H Husein‐ElAhmed… - Journal of the European …, 2024 - Wiley Online Library
Alopecia areata (AA) is an autoimmune disorder that affects the hair follicles, resulting in
patchy recurrent hair loss. A large body of evidence has demonstrated the favourable …

Hair regrowth in alopecia areata and re‐pigmentation in vitiligo in response to treatment: Commonalities and differences

HL Yamaguchi, Y Yamaguchi… - Journal of the European …, 2024 - Wiley Online Library
Both alopecia areata (AA) and vitiligo share common pathogenesis involving, interferon‐γ
(IFN‐γ) and interleukin‐15 (IL‐15) signalling pathways that activate cytotoxic CD8+ T …

[HTML][HTML] Efficacy and safety of baricitinib in patients with alopecia areata: Evidence to date

S Faria, E Freitas, T Torres - Drugs in Context, 2023 - ncbi.nlm.nih.gov
Alopecia areata (AA) is a chronic, tissue-specific autoimmune disorder, characterized by non-
scaring hair loss, with a global prevalence of approximately 2%. Typically, it affects a young …

In vitro hair growth-promoting effects of araliadiol via the p38/PPAR-γ signaling pathway in human hair follicle stem cells and dermal papilla cells

S Park, HW Park, DB Seo, DS Yoo… - Frontiers in Pharmacology, 2024 - frontiersin.org
Background Scalp hair plays a crucial role in social communication by expressing personal
appearance and self-identity. Consequently, hair loss often leads to a perception of …