[HTML][HTML] Can MRI measure myelin? Systematic review, qualitative assessment, and meta-analysis of studies validating microstructural imaging with myelin histology

A Lazari, I Lipp - Neuroimage, 2021 - Elsevier
Recent years have seen an increased understanding of the importance of myelination in
healthy brain function and neuropsychiatric diseases. Non-invasive microstructural magnetic …

[HTML][HTML] Myelin quantification with MRI: A systematic review of accuracy and reproducibility

CWJ van der Weijden, DV García, RJH Borra… - Neuroimage, 2021 - Elsevier
Objectives Currently, multiple sclerosis is treated with anti-inflammatory therapies, but these
treatments lack efficacy in progressive disease. New treatment strategies aim to repair …

[HTML][HTML] Decompose quantitative susceptibility mapping (QSM) to sub-voxel diamagnetic and paramagnetic components based on gradient-echo MRI data

J Chen, NJ Gong, KT Chaim, MCG Otaduy, C Liu - Neuroimage, 2021 - Elsevier
Purpose A method named DECOMPOSE-QSM is developed to decompose bulk
susceptibility measured with QSM into sub-voxel paramagnetic and diamagnetic …

Quantitative myelin imaging with MRI and PET: an overview of techniques and their validation status

CWJ van der Weijden, E Biondetti, IW Gutmann… - Brain, 2023 - academic.oup.com
Myelin is the protective sheath wrapped around axons, consisting of a phospholipid bilayer
with water between the wraps. The measurement of damage to the myelin sheaths, the …

Parkinson's disease multimodal imaging: F-DOPA PET, neuromelanin-sensitive and quantitative iron-sensitive MRI

F Depierreux, E Parmentier, L Mackels… - npj Parkinson's …, 2021 - nature.com
Parkinson's disease (PD) is a neurodegenerative synucleinopathy characterized by the
degeneration of neuromelanin (NM)-containing dopaminergic neurons and deposition of …

The influence of brain iron on myelin water imaging

C Birkl, AM Birkl-Toeglhofer, V Endmayr, R Höftberger… - Neuroimage, 2019 - Elsevier
With myelin playing a vital role in normal brain integrity and function and thus in various
neurological disorders, myelin sensitive magnetic resonance imaging (MRI) techniques are …

[HTML][HTML] Depth-wise profiles of iron and myelin in the cortex and white matter using χ-separation: A preliminary study

S Lee, HG Shin, M Kim, J Lee - NeuroImage, 2023 - Elsevier
The in-vivo profiling of iron and myelin across cortical depths and underlying white matter
has important implications for advancing knowledge about their roles in brain development …

Mapping human laryngeal motor cortex during vocalization

N Eichert, D Papp, RB Mars, KE Watkins - Cerebral Cortex, 2020 - academic.oup.com
The representations of the articulators involved in human speech production are organized
somatotopically in primary motor cortex. The neural representation of the larynx, however …

[HTML][HTML] Multiparameter MRI quantification of microstructural tissue alterations in multiple sclerosis

E Lommers, J Simon, G Reuter, G Delrue, D Dive… - NeuroImage: Clinical, 2019 - Elsevier
Objectives Conventional MRI is not sensitive to many pathological processes underpinning
multiple sclerosis (MS) ongoing in normal appearing brain tissue (NABT). Quantitative MRI …

Evaluation of the Blood‐Brain Barrier, Demyelination, and Neurodegeneration in Paramagnetic Rim Lesions in Multiple Sclerosis on 7 Tesla MRI

S Choi, S Lake, DM Harrison - Journal of Magnetic Resonance …, 2024 - Wiley Online Library
Background Paramagnetic rim lesions (PRLs) are associated with chronic inflammation in
multiple sclerosis (MS). 7‐Tesla (7T) magnetic resonance imaging (MRI) can evaluate the …