Regulatory T cells in gastric cancer: Key controllers from pathogenesis to therapy

I Negura, M Pavel-Tanasa, M Danciu - Cancer Treatment Reviews, 2023 - Elsevier
Gastric cancer (GC) is a highly aggressive malignancy that remains a significant contributor
to cancer-related mortality worldwide, despite a decline in incidence in recent years. Early …

[HTML][HTML] Bioactivity and bioavailability of carotenoids applied in human health: Technological advances and innovation

TG Bas - International Journal of Molecular Sciences, 2024 - mdpi.com
This article presents a groundbreaking perspective on carotenoids, focusing on their
innovative applications and transformative potential in human health and medicine …

New avenues for cancer immunotherapy: Cell-mediated drug delivery systems

H Zhang, A Grippin, M Sun, Y Ma, BYS Kim… - Journal of Controlled …, 2024 - Elsevier
Cancer research has become increasingly complex over the past few decades as
knowledge of the heterogeneity of cancer cells, their proliferative ability, and their tumor …

[HTML][HTML] Immunological Strategies in Gastric Cancer: How Toll-like Receptors 2,-3,-4, and-9 on Monocytes and Dendritic Cells Depend on Patient Factors?

M Kos, K Bojarski, P Mertowska, S Mertowski… - Cells, 2024 - mdpi.com
(1) Introduction: Toll-like receptors (TLRs) are key in immune response by recognizing
pathogen-associated molecular patterns (PAMPs) and damage-associated molecular …

[HTML][HTML] Effect of metabolic reprogramming on the immune microenvironment in gastric cancer

Z Shang, Z Ma, E Wu, X Chen, B Tuo, T Li… - Biomedicine & …, 2024 - Elsevier
Gastric cancer (GC) is a malignant tumor of the gastrointestinal tract with a high mortality rate
worldwide, a low early detection rate and a poor prognosis. The rise of metabolomics has …

The role of interleukin-6 classic and trans-signaling and interleukin-11 classic signaling in gastric cancer cells

J Runge, C Garbers, J Lokau - Contemporary Oncology/Współczesna …, 2024 - termedia.pl
Results: This study showed that different gastric tumor cell lines respond to IL-6 classic and
trans-signaling, but only slightly to stimulation with IL-11. We observed that monocyte-like …

Quantitative Analysis on Molecular Characteristics Evolution of Gastric Cancer Progression and Prognosis

Y Hu, X Lv, W Wei, X Li, K Zhang, L Zhu… - Advanced …, 2023 - Wiley Online Library
The dynamic changes of key biological characteristics from gastric low‐grade intraepithelial
neoplasia (LGIN) to high‐grade intraepithelial neoplasia (HGIN) to early gastric cancer …

Pivotal role of Helicobacter pylori virulence genes in pathogenicity and vaccine development

A Elbehiry, E Marzouk, A Abalkhail, W Sindi… - Frontiers in …, 2025 - frontiersin.org
One of the most prevalent human infections is Helicobacter pylori (H. pylori), which affects
more than half of the global population. Although H. pylori infections are widespread, only a …

Pathways and molecules for overcoming immunotolerance in metastatic gastrointestinal tumors

Q Gan, Y Li, Y Li, H Liu, D Chen, L Liu… - Frontiers in …, 2024 - frontiersin.org
Worldwide, gastrointestinal (GI) cancer is recognized as one of the leading malignancies
diagnosed in both genders, with mortality largely attributed to metastatic dissemination. It …

6-Phosphogluconate dehydrogenase inhibition arrests growth and induces apoptosis in gastric cancer via AMPK activation and oxidative stress

C Chen, P Du, Z Zhang, D Bao - Open Life Sciences, 2023 - degruyter.com
Poor outcomes in advanced gastric cancer necessitate alternative therapeutic strategies. 6-
Phosphogluconate dehydrogenase (6-PGDH), an enzyme that catalyzes the …