Recent advancements in the genetic engineering of microalgae

AE Sproles, FJ Fields, TN Smalley, CH Le, A Badary… - Algal Research, 2021 - Elsevier
The development of more sustainable food, feed, and bio-products is critical to mitigating the
environmental stresses facing our world today. Algae, which includes seaweeds, eukaryotic …

Isolation of industrial important bioactive compounds from microalgae

V Balasubramaniam, RDN Gunasegavan, S Mustar… - Molecules, 2021 - mdpi.com
Microalgae are known as a rich source of bioactive compounds which exhibit different
biological activities. Increased demand for sustainable biomass for production of important …

Emerging trends in genetic engineering of microalgae for commercial applications

SB Grama, Z Liu, J Li - Marine Drugs, 2022 - mdpi.com
Recently, microalgal biotechnology has received increasing interests in producing valuable,
sustainable and environmentally friendly bioproducts. The development of economically …

Chlamydomonas reinhardtii: A Factory of Nutraceutical and Food Supplements for Human Health

A Masi, F Leonelli, V Scognamiglio, G Gasperuzzo… - Molecules, 2023 - mdpi.com
Chlamydomonas reinhardtii (C. reinhardtii) is one of the most well-studied microalgae
organisms that revealed important information for the photosynthetic and metabolic …

Recent advancements and future perspectives of microalgae-derived pharmaceuticals

D Xia, W Qiu, X Wang, J Liu - Marine drugs, 2021 - mdpi.com
Microalgal cells serve as solar-powered factories that produce pharmaceuticals,
recombinant proteins (vaccines and drugs), and valuable natural byproducts that possess …

Biosynthesis of protein-based drugs using eukaryotic microalgae

Z Xie, J He, S Peng, X Zhang, W Kong - Algal Research, 2023 - Elsevier
Protein-based drugs are currently the fastest-growing category in the pharmaceutical
industry due to their high efficiency, low dosage, targeting, and low side effects. However …

Pre-erythrocytic vaccines against malaria

C Marques-da-Silva, K Peissig, SP Kurup - Vaccines, 2020 - mdpi.com
Malaria, caused by the protozoan Plasmodium, is a devastating disease with over 200
million new cases reported globally every year. Although immunization is arguably the best …

Harnessing the algal chloroplast for heterologous protein production

EA Cutolo, G Mandalà, L Dall'Osto, R Bassi - Microorganisms, 2022 - mdpi.com
Photosynthetic microbes are gaining increasing attention as heterologous hosts for the light-
driven, low-cost production of high-value recombinant proteins. Recent advances in the …

Environmental and nuclear influences on microalgal chloroplast gene expression

SE Carrera-Pacheco, B Hankamer, M Oey - Trends in Plant Science, 2023 - cell.com
Microalgal chloroplasts, such as those of the model organism Chlamydomonas reinhardtii,
are emerging as a new platform to produce recombinant proteins, including industrial …

Microalgal carbohydrates and proteins: Synthesis, extraction, applications, and challenges

A Shahid, F Khan, N Ahmad, M Farooq… - … biotechnology for food …, 2020 - Springer
Microalgae are a promising feedstock for renewable energy, nutraceuticals,
pharmaceuticals, and other high-value industrial products. The major components of algal …