Human platelet lysate: replacing fetal bovine serum as a gold standard for human cell propagation?
The essential physiological role of platelets in wound healing and tissue repair builds the
rationale for the use of human platelet derivatives in regenerative medicine. Abundant …
rationale for the use of human platelet derivatives in regenerative medicine. Abundant …
Human platelet lysate to substitute fetal bovine serum in hMSC expansion for translational applications: a systematic review
Background Foetal bovine serum (FBS), is the most commonly used culture medium additive
for in vitro cultures, despite its undefined composition, its potential immunogenicity and …
for in vitro cultures, despite its undefined composition, its potential immunogenicity and …
[HTML][HTML] Comparative analysis of human mesenchymal stem cells from bone marrow, adipose tissue, and umbilical cord blood as sources of cell therapy
HJ Jin, YK Bae, M Kim, SJ Kwon, HB Jeon… - International journal of …, 2013 - mdpi.com
Various source-derived mesenchymal stem cells (MSCs) have been considered for cell
therapeutics in incurable diseases. To characterize MSCs from different sources, we …
therapeutics in incurable diseases. To characterize MSCs from different sources, we …
Human alternatives to fetal bovine serum for the expansion of mesenchymal stromal cells from bone marrow
K Bieback, A Hecker, A Kocaömer, H Lannert… - Stem …, 2009 - academic.oup.com
Mesenchymal stromal cells (MSCs) are promising candidates for novel cell therapeutic
applications. For clinical scale manufacturing, human factors from serum or platelets have …
applications. For clinical scale manufacturing, human factors from serum or platelets have …
Mesenchymal stem and progenitor cells in regeneration: tissue specificity and regenerative potential
It has always been an ambitious goal in medicine to repair or replace morbid tissues for
regaining the organ functionality. This challenge has recently gained momentum through …
regaining the organ functionality. This challenge has recently gained momentum through …
Cryopreservation of human stem cells for clinical application: a review
CJ Hunt - Transfusion Medicine and Hemotherapy, 2011 - karger.com
Stem cells have been used in a clinical setting for many years. Haematopoietic stem cells
have been used for the treatment of both haematological and non-haematological disease; …
have been used for the treatment of both haematological and non-haematological disease; …
Epigenetic and in vivo comparison of diverse MSC sources reveals an endochondral signature for human hematopoietic niche formation
A Reinisch, N Etchart, D Thomas… - Blood, the Journal of …, 2015 - ashpublications.org
In the last decade there has been a rapid expansion in clinical trials using mesenchymal
stromal cells (MSCs) from a variety of tissues. However, despite similarities in morphology …
stromal cells (MSCs) from a variety of tissues. However, despite similarities in morphology …
Platelet lysate as a substitute for animal serum for the ex-vivo expansion of mesenchymal stem/stromal cells: present and future
The use of fetal bovine serum (FBS) as a cell culture supplement is discouraged by
regulatory authorities to limit the risk of zoonoses and xenogeneic immune reactions in the …
regulatory authorities to limit the risk of zoonoses and xenogeneic immune reactions in the …
Mesenchymal stromal cells: from discovery to manufacturing and commercialization
A Mizukami, K Swiech - Stem cells international, 2018 - Wiley Online Library
Over the last decades, mesenchymal stromal cells (MSC) have been the focus of intense
research by academia and industry due to their unique features. MSC can be easily isolated …
research by academia and industry due to their unique features. MSC can be easily isolated …
Isolation and characterization of mesenchymal stem cells from human umbilical cord blood: reevaluation of critical factors for successful isolation and high ability to …
X Zhang, M Hirai, S Cantero… - Journal of cellular …, 2011 - Wiley Online Library
Human umbilical cord blood (CB) is a potential source for mesenchymal stem cells (MSC)
capable of forming specific tissues, for example, bone, cartilage, or muscle. However …
capable of forming specific tissues, for example, bone, cartilage, or muscle. However …