Neurogenesis initiates during early development and it continues through later
developmental stages and in adult animals to enable expansion, remodeling, and …

Cranial placodes are evolutionary innovations of vertebrates. However, they most likely
evolved by redeployment, rewiring and diversification of preexisting cell types and …

Placodes and neural crests represent defining features of vertebrates, yet their relationship
remains unclear despite extensive investigation,–. Here we use a combination of lineage …

The origin of the bilaterian head is a fundamental question for the evolution of animal body
plans. The head of bilaterians develops at the anterior end of their primary body axis and is …

Glioblastoma (GBM) is the most common and lethal brain tumor in adults. Due to its fast
proliferation, diffusive growth and therapy resistance survival times are less than two years …

The dmrt6 gene has been isolated from tetrapods and recently from a coelacanth, Latimeria
chalumnae. Its evolutionary history and exact function remain unclear. In the present study …

Doublesex and Mab-3-related transcription factor (DMRT) gene family is extensively known
for its contribution in sex determination and differentiation across phyla. Here we report the …

Abstract The family of Doublesex-Mab-3 Related Transcription factors (DMRTs) includes key
regulators of sexual differentiation and neurogenesis. To help understand the functional …

Dmrt genes encode a large family of transcription factors characterized by the presence of a
DM domain, an unusual zinc finger DNA binding domain. While Dmrt genes are well known …

The molecular mechanism of sex determination changed rapidly during evolution among
phyla. One exception is the Dmrt (doublesex and mab-3 related transcription factor) family …