Protein cages: from fundamentals to advanced applications
Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …
Ferritin: a promising nanoreactor and nanocarrier for bionanotechnology
The essence of bionanotechnology lies in the application of nanotechnology/nanomaterials
to solve the biological problems. Quantum dots and nanoparticles hold potential biomedical …
to solve the biological problems. Quantum dots and nanoparticles hold potential biomedical …
Functional ferritin nanoparticles for biomedical applications
Ferritin, a major iron storage protein with a hollow interior cavity, has been reported recently
to play many important roles in biomedical and bioengineering applications. Owing to the …
to play many important roles in biomedical and bioengineering applications. Owing to the …
Iron, copper, and zinc homeostasis: Physiology, physiopathology, and nanomediated applications
Understanding of how the human organism functions has preoccupied researchers in
medicine for a very long time. While most of the mechanisms are well understood and …
medicine for a very long time. While most of the mechanisms are well understood and …
Vertasile ferritin nanocages: applications in detection and bioimaging
Y Chen, C Xu, M Sun, G Zhao, Z Wang, C Lv - Biosensors and …, 2024 - Elsevier
Food safety and human health remain significant concerns in the food industry. Detecting
food contaminants and diagnosing diseases are critical aspects. Ferritin, an iron storage …
food contaminants and diagnosing diseases are critical aspects. Ferritin, an iron storage …
Spatially controlled assembly of affinity ligand and enzyme cargo enables targeting ferritin nanocarriers to caveolae
VV Shuvaev, M Khoshnejad, KW Pulsipher… - Biomaterials, 2018 - Elsevier
One of the goals of nanomedicine is targeted delivery of therapeutic enzymes to the sub-
cellular compartments where their action is needed. Endothelial caveolae-derived …
cellular compartments where their action is needed. Endothelial caveolae-derived …
Ferritin-based anticancer metallodrug delivery: Crystallographic, analytical and cytotoxicity studies
The encapsulation of anticancer metal-based drugs within a protein nanocage represents a
valuable strategy to improve the efficacy and selectivity of these compounds towards cancer …
valuable strategy to improve the efficacy and selectivity of these compounds towards cancer …
Nephron number and its determinants: a 2020 update
JR Charlton, EJ Baldelomar, DM Hyatt, KM Bennett - Pediatric Nephrology, 2021 - Springer
Studies of human nephron number have been conducted for well over a century and have
uncovered a large variability in nephron number. However, the mechanisms influencing …
uncovered a large variability in nephron number. However, the mechanisms influencing …
Nanotechnology‐based strategies for early diagnosis of central nervous system disorders
Central nervous system (CNS) disorders feature the progressive and selective loss of
normal brain functions. CNS disorders often include an irreversible physiological and …
normal brain functions. CNS disorders often include an irreversible physiological and …
Nephron loss detected by MRI following neonatal acute kidney injury in rabbits
JR Charlton, EJ Baldelomar, KA deRonde… - Pediatric …, 2020 - nature.com
Background Acute kidney injury affects nearly 30% of preterm neonates in the intensive care
unit. We aimed to determine whether nephrotoxin-induced AKI disrupted renal development …
unit. We aimed to determine whether nephrotoxin-induced AKI disrupted renal development …