Recent advances to enhance the immunomodulatory potential of mesenchymal stem cells

M Sarsenova, Y Kim, K Raziyeva, B Kazybay… - Frontiers in …, 2022 - frontiersin.org
Considering the unique therapeutic potential of mesenchymal stem cells (MSCs), including
their immunosuppressive and immunomodulatory properties as well as their ability to …

Breaking the graft-versus-host-disease barrier: Mesenchymal stromal/stem cells as precision healers

M Mendiratta, M Mendiratta, S Mohanty… - International Reviews …, 2024 - Taylor & Francis
Abstract Mesenchymal Stromal/Stem Cells (MSCs) are multipotent, non-hematopoietic
progenitor cells with a wide range of immune modulation and regenerative potential which …

The autophagy protein Def8 is altered in Alzheimer's disease and Aβ42-expressing Drosophila brains

S Oyarce-Pezoa, GG Rucatti, F Muñoz-Carvajal… - Scientific Reports, 2023 - nature.com
Alzheimer's disease (AD) is the most common neurodegenerative disorder, characterized by
protein accumulation in the brain as a main neuropathological hallmark. Among them, Aβ42 …

The autophagy protein RUBCNL/PACER represses RIPK1 kinase-dependent apoptosis and necroptosis

D Rojas-Rivera, S Beltrán, F Muñoz-Carvajal… - Autophagy, 2024 - Taylor & Francis
Mesenchymal stem cells (MSCs) are used in cell therapy; nonetheless, their application is
limited by their poor survival after transplantation in a proinflammatory microenvironment …

Mesenchymal stem cells: a novel therapeutic approach for feline inflammatory bowel disease

Q Xie, S Gong, J Cao, A Li, MF Kulyar, B Wang… - Stem Cell Research & …, 2024 - Springer
Background Inflammatory bowel disease (IBD) poses a significant and growing global
health challenge, affecting both humans and domestic cats. Research on feline IBD has not …

Overexpression of autophagy enhancer PACER/RUBCNL in neurons accelerates disease in the SOD1G93A ALS mouse model

L Labrador, L Rodriguez, S Beltran, F Hernandez… - Biological Research, 2024 - Springer
Amyotrophic lateral sclerosis (ALS) is a debilitating and fatal paralytic disorder associated
with motor neuron death. Mutant superoxide dismutase 1 (SOD1) misfolding and …

Different Levels of Autophagy Activity in Mesenchymal Stem Cells Are Involved in the Progression of Idiopathic Pulmonary Fibrosis

H Tao, Q Lv, J Zhang, L Chen, Y Yang… - Stem Cells …, 2024 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is an age‐related lung interstitial disease that occurs
predominantly in people over 65 years of age and for which there is a lack of effective …

自噬与间充质干细胞治疗神经退行性病的相互作用

肖怡, 卢硕, 葛丽特, 卢明 - 中国组织工程研究, 2024 - cjter.com
自噬与间充质干细胞治疗神经退行性病的相互作用 Page 1 Chinese Journal of Tissue Engineering
Research|Vol 28|No.19|July 2024|3111 中国组织工程研究 Chinese Journal of Tissue …

Bone marrow mesenchymal stem cell-induced autophagy ameliorates TNBS-induced experimental colitis by downregulating the NLRP3 inflammasome.

J Fu, X Feng, J Wei, X Geng, Y Gong, F Li… - …, 2023 - search.ebscohost.com
Background: This study aimed to elucidate the potential mechanisms through which bone
marrow-derived mesenchymal stem cells (BM-MSCs) may be effective in alleviating …

Interaction between autophagy and mesenchymal stem cells in treatment of neurodegenerative diseases

Y Xiao, S Lu, L Ge, M Lu - Chinese Journal of Tissue Engineering …, 2024 - cjter.com
BACKGROUND: Neuronal autophagy disorder and abnormal protein aggregation are the
main pathological changes of neurodegenerative diseases. The relationship and interaction …