Molecular docking as a tool for the discovery of molecular targets of nutraceuticals in diseases management

PC Agu, CA Afiukwa, OU Orji, EM Ezeh, IH Ofoke… - Scientific Reports, 2023 - nature.com
Molecular docking is a computational technique that predicts the binding affinity of ligands to
receptor proteins. Although it has potential uses in nutraceutical research, it has developed …

Review on the use of Molecular Docking as the First Line Tool in Drug Discovery and Development.

RN Sahoo, S Pattanaik, G Pattnaik… - Indian Journal of …, 2022 - search.ebscohost.com
Molecular docking has now become a novel approach for drug discovery in recent years.
Computer-aided drug design is an area that is rapidly growing and has seen many …

Physicochemical Characterization, Molecular Docking, and In Vitro Dissolution of Glimepiride–Captisol Inclusion Complexes

A Pal, S Roy, A Kumar, S Mahmood, N Khodapanah… - ACS …, 2020 - ACS Publications
This present study investigated the effect of Captisol, a chemically modified cyclodextrin, on
the in vitro dissolution of glimepiride. We prepared glimepiride–Captisol complexes of …

Development and characterization of natural product derived macromolecules based interpenetrating polymer network for therapeutic drug targeting

A Biswas, S Mondal, SK Das, A Bose, S Thomas… - ACS …, 2021 - ACS Publications
Interpenetrating polymer network (IPN)-based bead formulations were exploited by cross-
linking different hydrophilic polymers in different combinations and at different ratios …

Drug-in-mucoadhesive type film for ocular anti-inflammatory potential of amlodipine: Effect of sulphobutyl-ether-beta-cyclodextrin on permeation and molecular …

A Nanda, RN Sahoo, A Pramanik, R Mohapatra… - Colloids and Surfaces B …, 2018 - Elsevier
Mucoadhesive type ocular film has been prepared for studying the anti-inflammatory
potential of amlodipine (AML) on carrageenan-induced rabbit model and the effect of …

Bentonite clay incorporated topical film formulation for delivery of trimetazidine: Control of ocular pressure and in vitro-in vivo correlation

R Swain, S Nandi, RN Sahoo, SS Swain… - Journal of Drug Delivery …, 2022 - Elsevier
Bentonite clay based film formulation has been prepared for topical delivery of trimetazidine
(TZ) for the control of ocular pressure. Trimetazidine ophthalmic film formulation has been …

Physicochemical characterization and in vitro dissolution performance of ibuprofen-Captisol®(sulfobutylether sodium salt of β-CD) inclusion complexes

SK Das, N Kahali, A Bose, J Khanam - Journal of molecular liquids, 2018 - Elsevier
The aim of the present research work was to explore the impact of ibuprofen-captisol®(
sulfobutylether sodium salt of β-CD) inclusion complexes on in vitro dissolution …

Ocular permeation and sustained anti-inflammatory activity of dexamethasone from kaolin nanodispersion hydrogel system

A Pramanik, RN Sahoo, A Nanda… - Current Eye …, 2018 - Taylor & Francis
Purpose: Kaolin can adhere to the mucosa and protect it by absorbing toxins, bacteria, and
viruses. Ocular delivery and anti-inflammatory activity of dexamethasone hydrogel system …

[PDF][PDF] Infrared Spectroscopy for Analysis of Co-processed Ibuprofen and Magnesium Trisilicate at Milling and Freeze Drying.

M Acharya, S Mishra, RN Sahoo… - Acta Chimica …, 2017 - researchgate.net
Assessment of interactions of ibuprofen and magnesium trisilicate after co-processing has
been carried out by infrared spectroscopy. Dry-state ball-milling and, aqueous state …

Vildagliptin plasticized hydrogel film in the control of ocular inflammation after topical application: study of hydration and erosion behaviour

S Nandi, A Ojha, A Nanda, RN Sahoo… - Zeitschrift für …, 2022 - degruyter.com
Vildagliptin (VID) is a dipeptidyl peptidase-4 (DPP-4) inhibitor used in controlling blood
glucose level in type 2 diabetes. Vildagliptin improves beta cells function and is also …