White adipose tissue is one of the largest organs of the body. It plays a key role in whole‐
body energy status and metabolism; it not only stores excess energy but also secretes …

Prevalence rates of pediatric obesity continue to rise worldwide. Adipose tissue (AT)
development and expansion initiate in the fetus and extend throughout the lifespan. This …

Obesity has dramatically increased during the last decades and is currently one of the most
serious global health problems. We present a hypothesis that obesity is a neuro-behavioral …

Understanding the consequences of individual transcriptome variation is fundamental to
deciphering human biology and disease. We implement a statistical framework to quantify …

Tissue-specific mechanisms prompting obesity-related development complications in
humans remain unclear. We apply multiomics analyses of subcutaneous adipose tissue and …

The purpose of this review is to provide a detailed and updated description of the
FinnTwin16 (FT16) study and its future directions. The Finnish Twin Cohort comprises three …

White adipose tissue (WAT) is an important endocrine organ that regulates systemic energy
metabolism. In metabolically unhealthy obesity, adipocytes become dysfunctional through …

Albeit a consistent body of evidence supports the notion that genes influence
cardiometabolic features and outcomes, the “non-genetic regulation” of this process is …

Significance: The prevalence of obesity and cardiometabolic phenotypes is alarmingly
increasing across the globe and is associated with atherosclerotic vascular complications …

Context Mitochondria are essential for cellular energy homeostasis, yet their role in
subcutaneous adipose tissue (SAT) during different types of weight-loss interventions …