Local drug delivery challenges and innovations in spinal neurosurgery
C Karavasili, T Young, J Francis, J Blanco… - Journal of Controlled …, 2024 - Elsevier
The development of novel therapeutics in the field of spinal neurosurgery faces a litany of
translational challenges. Achieving precise drug targeting within the confined spaces …
translational challenges. Achieving precise drug targeting within the confined spaces …
Systemic inhibition of bone morphogenetic protein 1.3 as a possible treatment for laminin-related congenital muscular dystrophy
Congenital muscular dystrophy (CMD) is a group of rare neuromuscular disorders typically
characterized by the onset of symptoms at birth or within the first two years of life. CMDs are …
characterized by the onset of symptoms at birth or within the first two years of life. CMDs are …
Comparison of synthetic ceramic products formulated with autologous blood coagulum containing rhBMP6 for induction of bone formation
Purpose Osteogrow, an osteoinductive device containing recombinant human Bone
Morphogenetic Protein 6 (rhBMP6) in autologous blood coagulum, is a novel therapeutic …
Morphogenetic Protein 6 (rhBMP6) in autologous blood coagulum, is a novel therapeutic …
Calcium phosphate ceramics combined with rhBMP6 within autologous blood coagulum promote posterolateral lumbar fusion in sheep
Posterolateral spinal fusion (PLF) is a procedure used for the treatment of degenerative
spine disease. In this study we evaluated Osteogrow-C, a novel osteoinductive device …
spine disease. In this study we evaluated Osteogrow-C, a novel osteoinductive device …
Design and development of the additively manufactured Zn-Li scaffolds for posterolateral lumbar fusion
Spinal fusion is a commonly used technique to treat acute and chronic spinal diseases by
fusion of the adjacent vertebrae, aiming at achieving stability and eliminating the mobility of …
fusion of the adjacent vertebrae, aiming at achieving stability and eliminating the mobility of …
[HTML][HTML] rhBMP6 in autologous blood coagulum is a preferred osteoinductive device to rhBMP2 on bovine collagen sponge in the rat ectopic bone formation assay
Osteoinductive BMPs require a suitable delivery system for treating various pathological
conditions of the spine and segmental bone defects. INFUSE, the only commercially …
conditions of the spine and segmental bone defects. INFUSE, the only commercially …
[PDF][PDF] State-of-the-art of the Bone Morphogenetic Protein research field: 13th International BMP Confer-ence
Te 13th International BMP Conference was held in October 2022 in Dubrovnik. Te
conference was attended by more than 240 participants from North America, Europe, Asia …
conference was attended by more than 240 participants from North America, Europe, Asia …
A simple rodent subcutaneous assay for identification of new osteoinductive molecules: The key method for screening of novel bone regeneration implants
A simple rodent subcutaneous assay for identification of new osteoinductive molecules: The
key method for screening of novel bon Page 1 REviEw ARticlE RAD 553. Medical Sciences …
key method for screening of novel bon Page 1 REviEw ARticlE RAD 553. Medical Sciences …
Exploration of new platforms and potentials in regenerative medicine
Sažetak Regenerative medicine is focused on the regeneration of various tissues and
organs through the development of innovative therapeutic strategies and devices. Center of …
organs through the development of innovative therapeutic strategies and devices. Center of …
[PDF][PDF] A simple rodent subcutaneous assay for iden-tification of new osteoinductive mol-ecules: The key method for screening of novel bone regeneration implants …
N Stokovic - This is an open-access article distributed under the …, 2022 - rad-med.com
Abstract Treatment of large bone defects and degenerative diseases of the spine is among
the most challenging and still unresolved issues in clinical medicine. Therefore, substantial …
the most challenging and still unresolved issues in clinical medicine. Therefore, substantial …