Abstract The EGFR/PI3K/PTEN/Akt/mTORC1/GSK-3 pathway plays prominent roles in
malignant transformation, prevention of apoptosis, drug resistance and metastasis. The …

The traditional Mediterranean Diet constitutes a food model that refers to the dietary patterns
of the population living in countries bordering the Mediterranean Sea in the early 1960s. A …

Activation of peroxisome proliferator-activated receptor gamma (PPARγ) elicits anti-
proliferative effects on different tumor cells, including those derived from breast cancer …

Simple Summary Breast cancer represents the most frequently diagnosed carcinoma and
the leading cause of cancer death in women. Despite advances achieved in systemic …

Obesity induces numerous physiological changes that can impact cancer risk and patient
response to therapy. Obese patients with cervical cancer have been reported to have …

Mitochondria are semi-autonomous organelles that play essential roles in cellular
metabolism and programmed cell death pathways. Genomic, functional and structural …

Background The omega-3 docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA)
may form conjugates with amines that have potential health benefits against common …

Over the last decades a renewed interest in n− 3 very long polyunsaturated fatty acids
(PUFAs), derived mainly from fish oils in the human diet, has been observed because of …

Abstract Stromal Derived Factor-1α (SDF-1α) and its cognate receptor CXCR4 play a key
role in mediating breast cancer cell invasion and metastasis. Therefore, drugs able to inhibit …

Simple Summary Triple-negative breast cancer (TNBC) is associated with a generally poor
breast cancer outcome, intensifying the need for novel therapeutic strategies beyond …