Frailty, a consequence of the interaction of the aging process and certain chronic diseases,
compromises functional outcomes in the elderly and substantially increases their risk for …

Sarcopenia is a loss of muscle mass and function in the elderly that reduces mobility,
diminishes quality of life, and can lead to fall-related injuries, which require costly …

The world population is ageing rapidly. As society ages, the incidence of physical limitations
is dramatically increasing, which reduces the quality of life and increases healthcare …

Many physiological changes occur with aging. These changes often, directly or indirectly,
result in a deterioration of the quality of life and even in a shortening of life expectancy …

Obesity is associated with functional limitations in muscle performance and increased
likelihood of developing a functional disability such as mobility, strength, postural and …

As we age, there is an age-related loss in skeletal muscle mass and strength, known as
sarcopenia. Sarcopenia results in a decrease in mobility and independence, as well as an …

Obesity has been associated with increased production of reactive oxygen species (ROS),
which may be involved in the development of cardiovascular disease and type 2 diabetes …

Ageing causes loss of function in tissues and organs, is accompanied by a chronic
inflammatory process and affects life‐and healthspan. Calorie restriction (CR) is a non …

Aging is associated with a progressive loss of muscle mass and strength and a decline in
neurophysiological functions. Age-related neuromuscular junction (NMJ) plays a key role in …

Background Older adults experience considerable muscle and bone loss that are closely
interconnected. The efficacy of progressive resistance training programs to concurrently …