Bone defects are among the most common damages in human medicine. Due to limitations
and challenges in the area of bone healing, the research field has turned into a hot topic …

Enthesis, the interfacial tissue between a tendon/ligament and bone, exhibits a complex
histological transition from soft to hard tissue, which significantly complicates its repair and …

Cell sheet engineering, a scaffold-free tissue fabrication technique, has proven to be an
important breakthrough technology in regenerative medicine. Over the past two decades …

Soft tissue regeneration holds significant promise for addressing various clinical challenges,
ranging from craniofacial and oral tissue defects to blood vessels, muscle, and fibrous tissue …

Tendon–bone interface is prevalent in the human body. It is divided into four zones: tendon
(soft tissue), unmineralized fibrocartilage, mineralized fibrocartilage, and bone (hard tissue) …

Background The tendon or ligament is attached to the bone by a triphasic but continuous
area of heterogeneous tissue called the tendon-bone interface (TBI). The rapid and …

Background: Adipose-derived stem cell (ADSC) sheets have been shown to promote tendon-
to-bone healing. However, conventional laboratory preparation methods for ADSC sheets …

During developmental processes, cells frequently condense along a preferred axis, creating
columnar arrangements—a pivotal step in shaping elongating tissue structures and …