Embracing the era of antimicrobial peptides with marine organisms
Covering: 2018 to Jun of 2023 The efficiency of traditional antibiotics has been undermined
by the proliferation of antibiotic-resistant pathogenic microorganisms, necessitating the …
by the proliferation of antibiotic-resistant pathogenic microorganisms, necessitating the …
Marine resources offer new compounds and strategies for the treatment of skin and soft tissue infections
A Labes - Marine Drugs, 2023 - mdpi.com
Bioprospecting of the marine environment for drug development has gained much attention
in recent years owing to its massive chemical and biological diversity. Drugs for the …
in recent years owing to its massive chemical and biological diversity. Drugs for the …
A review of current antibiotic resistance and promising antibiotics with novel modes of action to combat antibiotic resistance
L Chen, S Kumar, H Wu - Archives of Microbiology, 2023 - Springer
The emergence and transmission of antibiotic resistance is a global public health crisis with
significant burden on healthcare systems, resulting in high mortality and economic costs. In …
significant burden on healthcare systems, resulting in high mortality and economic costs. In …
“AMP plus”: Immunostimulant-Inspired Design Based on Chemotactic Motif-(PhHAhPH)n
Y Zhu, Y Xu, J Yan, Y Fang, N Dong… - ACS Applied Materials & …, 2023 - ACS Publications
Ability to stimulate antimicrobial immunity has proven to be a useful therapeutic strategy in
treating infections, especially in the face of increasing antibiotic resistance. Natural …
treating infections, especially in the face of increasing antibiotic resistance. Natural …
Novel antimicrobial peptide DvAMP serves as a promising antifungal agent against Cryptococcus neoformans
L Yang, Z Tian, W Zhao, J Zhang, C Tian, L Zhou… - Bioorganic …, 2023 - Elsevier
Cryptococcus neoformans is an important opportunistic human fungal pathogen that causes
cryptococcosis in immunocompromised patients. However, the number of drugs for the …
cryptococcosis in immunocompromised patients. However, the number of drugs for the …
Thinking on the construction of antimicrobial peptide databases: Powerful tools for the molecular design and screening
K Zhang, D Teng, R Mao, N Yang, Y Hao… - International Journal of …, 2023 - mdpi.com
With the accelerating growth of antimicrobial resistance (AMR), there is an urgent need for
new antimicrobial agents with low or no AMR. Antimicrobial peptides (AMPs) have been …
new antimicrobial agents with low or no AMR. Antimicrobial peptides (AMPs) have been …
Helminthic host defense peptides: using the parasite to defend the host
Parasitic helminths are destined to share niches with a variety of microbiota that inevitably
influence their interaction with the host. To modulate the microbiome for their benefit and …
influence their interaction with the host. To modulate the microbiome for their benefit and …
Simulation study of the effect of antimicrobial peptide associations on the mechanism of action with bacterial and eukaryotic membranes
Antimicrobial peptides (AMPs) can be directed to specific membranes based on differences
in lipid composition. In this study, we performed atomistic and coarse-grained simulations of …
in lipid composition. In this study, we performed atomistic and coarse-grained simulations of …
Relating molecular dynamics simulations to functional activity for gly-rich membranolytic helical kiadin peptides
Kiadins are in silico designed peptides with a strong similarity to di PGLa-H, a tandem
sequence of PGLa-H (KIAKVALKAL) and with single, double or quadruple glycine …
sequence of PGLa-H (KIAKVALKAL) and with single, double or quadruple glycine …
Dual‐Mechanism Peptide SR25 has Broad Antimicrobial Activity and Potential Application for Healing Bacteria‐infected Diabetic Wounds
XY Luo, CM Hu, Q Yin, XM Zhang, ZZ Liu… - Advanced …, 2024 - Wiley Online Library
The rise of antibiotic resistance poses a significant public health crisis, particularly due to
limited antimicrobial options for the treatment of infections with Gram‐negative pathogens …
limited antimicrobial options for the treatment of infections with Gram‐negative pathogens …