Objectives: the conditions of obesity and overweight pose a major risk for a number of
comorbidities, including clinical syndromes resulting from atherosclerotic disease. Recent …

Multiple sclerosis (MS), a chronic inflammatory and demyelinating disease of the central
nervous system (CNS), is a major clinical and societal problem, which has a tremendous …

Background Reports on body mass index (BMI) trajectories from childhood into late
adolescence, their determinants, and subsequent cardiometabolic risk markers, particularly …

Prader-Willi syndrome (PWS) is the predominant genetic cause of obesity in humans.
Recent clinical reports have suggested that micro-deletion of the Snord116 gene cluster can …

In a mouse model of diet-induced obesity, this study determined if two exercise prescriptions
with equivalent time and distance covered,[constant-moderate endurance (END) and high …

Background The interplay between adiponectin and resistin, the two adipokines of opposite
effects, may determine the metabolic profile of obese individuals and development of obesity …

Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease
characterized by the loss of upper cortical and lower motor neurons. ALS causes death …

Metabolic syndrome is associated with both schizophrenia and antipsychotic medication,
especially clozapine, with alterations in inflammatory cytokines and adipokines. However …

Exercise regimens may have differing effects in the presence of obesity. In addition to being
fat derived, adiponectin has recently been described as a myokine that regulates insulin …

Background Obesity is complicated by low-grade chronic inflammation characterised by
increases in inflammatory proteins and cells in peripheral blood. It has been known that …