Manganese neurotoxicity: behavioral disorders associated with dysfunctions in the basal ganglia and neurochemical transmission

S Bouabid, A Tinakoua… - Journal of …, 2016 - Wiley Online Library
Manganese (Mn) is an essential element required for many physiological functions. While it
is essential at physiological levels, excessive accumulation of Mn in the brain causes severe …

Intellectual impairment in school-age children exposed to manganese from drinking water

MF Bouchard, S Sauvé, B Barbeau… - Environmental …, 2011 - ehp.niehs.nih.gov
Background Manganese is an essential nutrient, but in excess it can be a potent
neurotoxicant. Despite the common occurrence of manganese in groundwater, the risks …

Are there common biochemical and molecular mechanisms controlling manganism and parkisonism

JA Roth - Neuromolecular medicine, 2009 - Springer
Over the past several decades there has been considerable progress in our basic
knowledge as to the mechanisms and factors regulating Mn toxicity. The disorder known as …

Manganese exposure from drinking water and children's academic achievement

K Khan, GA Wasserman, X Liu, E Ahmed, F Parvez… - Neurotoxicology, 2012 - Elsevier
Drinking water manganese (WMn) is a potential threat to children's health due to its
associations with a wide range of outcomes including cognitive, behavioral and …

[HTML][HTML] Patterns of multisite pain and associations with risk factors

D Coggon, G Ntani, KT Palmer, VE Felli, R Harari… - Pain®, 2013 - Elsevier
To explore definitions for multisite pain, and compare associations with risk factors for
different patterns of musculoskeletal pain, we analysed cross-sectional data from the …

Low level exposure to manganese from drinking water and cognition in school-age children

MF Bouchard, C Surette, P Cormier, D Foucher - Neurotoxicology, 2018 - Elsevier
Abstract Background Manganese (Mn) is an element found in the environment and certain
geographic areas have elevated concentrations in soil and water du to natural conditions or …

Airborne manganese exposure and neurobehavior in school-aged children living near a ferro-manganese alloy plant

JLG Rodrigues, CFS Araújo, NR Dos Santos… - Environmental …, 2018 - Elsevier
Excessive exposure to Mn can lead to its accumulation in the brain with neurotoxic
consequences. In children, elevated Mn has been associated with deficits in certain …

[HTML][HTML] Environmental manganese exposure and associations with memory, executive functions, and hyperactivity in Brazilian children

CF de Carvalho, Y Oulhote, M Martorelli… - Neurotoxicology, 2018 - Elsevier
Manganese (Mn) is an essential element, however high levels of Mn have been associated
with lower neuropsychological performance and behavioral problems in children. We …

Manganese exposure and cognitive performance: A meta-analytical approach

T Vlasak, T Dujlovic, A Barth - Environmental Pollution, 2023 - Elsevier
Occupational manganese exposure is associated with serious health concerns, ultimately
leading to an illness called manganism. Competing meta-analytic results were published …

Hypermanganesemia due to mutations in SLC39A14: further insights into Mn deposition in the central nervous system

L Marti-Sanchez, JD Ortigoza-Escobar… - Orphanet journal of rare …, 2018 - Springer
Abstract Background The SLC39A14, SLC30A10 and SLC39A8 are considered to be key
genes involved in manganese (Mn) homeostasis in humans. Mn levels in plasma and urine …