[HTML][HTML] Factors and pathways modulating endothelial cell senescence in vascular aging
Aging causes a progressive decline in the structure and function of organs. With advancing
age, an accumulation of senescent endothelial cells (ECs) contributes to the risk of …
age, an accumulation of senescent endothelial cells (ECs) contributes to the risk of …
[HTML][HTML] Vascular endothelial senescence: pathobiological insights, emerging long noncoding RNA targets, challenges and therapeutic opportunities
X Sun, MW Feinberg - Frontiers in Physiology, 2021 - frontiersin.org
Cellular senescence is a stable form of cell cycle arrest in response to various stressors.
While it serves as an endogenous pro-resolving mechanism, detrimental effects ensue when …
While it serves as an endogenous pro-resolving mechanism, detrimental effects ensue when …
[HTML][HTML] LncRNA and circRNA in patients with non-alcoholic fatty liver disease: a systematic review
Q Zeng, CH Liu, D Wu, W Jiang, N Zhang, H Tang - Biomolecules, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is currently the most common cause of chronic
liver disease worldwide. Early identification and prompt treatment are critical to optimize …
liver disease worldwide. Early identification and prompt treatment are critical to optimize …
[HTML][HTML] Long noncoding RNAs in the pathogenesis of insulin resistance
W Yang, Y Lyu, R Xiang, J Yang - International journal of molecular …, 2022 - mdpi.com
Insulin resistance (IR), designated as the blunted response of insulin target tissues to
physiological level of insulin, plays crucial roles in the development and progression of …
physiological level of insulin, plays crucial roles in the development and progression of …
[HTML][HTML] Role of long non-coding RNAs and the molecular mechanisms involved in insulin resistance
VA Tello-Flores, FO Beltrán-Anaya… - International Journal of …, 2021 - mdpi.com
Long non-coding RNAs (lncRNAs) are single-stranded RNA biomolecules with a length of>
200 nt, and they are currently considered to be master regulators of many pathological …
200 nt, and they are currently considered to be master regulators of many pathological …
[HTML][HTML] Regulation of oxidative stress by long non-coding RNAs in vascular complications of diabetes
Diabetes mellitus is a well-known metabolic disorder with numerous complications, such as
macrovascular diseases (eg, coronary heart disease, diabetic cardiomyopathy, stroke, and …
macrovascular diseases (eg, coronary heart disease, diabetic cardiomyopathy, stroke, and …
[HTML][HTML] Dietary Curcumin Attenuates Hepatic Cellular Senescence by Suppressing the MAPK/NF-κB Signaling Pathway in Aged Mice
Dietary interventions with bioactive compounds have been found to suppress the
accumulation of senescent cells and senescence-associated secretory phenotypes …
accumulation of senescent cells and senescence-associated secretory phenotypes …
[HTML][HTML] Metabolic regulation of endothelial senescence
NT Le - Frontiers in Cardiovascular Medicine, 2023 - frontiersin.org
Endothelial cell (EC) senescence is increasingly recognized as a significant contributor to
the development of vascular dysfunction and age-related disorders and diseases, including …
the development of vascular dysfunction and age-related disorders and diseases, including …
[HTML][HTML] LncRNA-COX2 inhibits fibroblast activation and epidural fibrosis by targeting EGR1
Rationale: Epidural fibrosis is one of the contributors to failed back surgery syndrome
(FBSS) with a high incidence of about 80,000 cases per year. The fibrosis spreads from the …
(FBSS) with a high incidence of about 80,000 cases per year. The fibrosis spreads from the …
[HTML][HTML] Emerging role of non-coding RNAs in senescence
Senescence is defined as a gradual weakening of functional features of a living organism.
Cellular senescence is a process that is principally aimed to remove undesirable cells by …
Cellular senescence is a process that is principally aimed to remove undesirable cells by …