Aging causes a progressive decline in the structure and function of organs. With advancing
age, an accumulation of senescent endothelial cells (ECs) contributes to the risk of …

Cellular senescence is a stable form of cell cycle arrest in response to various stressors.
While it serves as an endogenous pro-resolving mechanism, detrimental effects ensue when …

Non-alcoholic fatty liver disease (NAFLD) is currently the most common cause of chronic
liver disease worldwide. Early identification and prompt treatment are critical to optimize …

Insulin resistance (IR), designated as the blunted response of insulin target tissues to
physiological level of insulin, plays crucial roles in the development and progression of …

Long non-coding RNAs (lncRNAs) are single-stranded RNA biomolecules with a length of>
200 nt, and they are currently considered to be master regulators of many pathological …

Diabetes mellitus is a well-known metabolic disorder with numerous complications, such as
macrovascular diseases (eg, coronary heart disease, diabetic cardiomyopathy, stroke, and …

Dietary interventions with bioactive compounds have been found to suppress the
accumulation of senescent cells and senescence-associated secretory phenotypes …

Endothelial cell (EC) senescence is increasingly recognized as a significant contributor to
the development of vascular dysfunction and age-related disorders and diseases, including …

Rationale: Epidural fibrosis is one of the contributors to failed back surgery syndrome
(FBSS) with a high incidence of about 80,000 cases per year. The fibrosis spreads from the …

Senescence is defined as a gradual weakening of functional features of a living organism.
Cellular senescence is a process that is principally aimed to remove undesirable cells by …