Omega‐6 (n‐6) polyunsaturated fatty acids (PUFA)(eg, arachidonic acid (AA)) and omega‐3
(n‐3) PUFA (eg, eicosapentaenoic acid (EPA)) are precursors to potent lipid mediator …

Many clinical and animal studies demonstrate the importance of long-chain polyunsaturated
fatty acids (LCPUFA) in neural development and neurodegeneration. This review will focus …

Lower brain glucose metabolism is present before the onset of clinically measurable
cognitive decline in two groups of people at risk of Alzheimer's disease---carriers of …

Recent advances in functional foods and nutraceuticals have emphasized the beneficial
impact of bioactive molecules on human health and longevity. The omega-3 (ω-3) long …

Objective: Randomized trials of omega-3 polyunsaturated fatty acid (PUFA) treatment for
depression have differed in outcome. Recent meta-analyses ascribe discrepancies to …

There is considerable interest in the potential impact of several polyunsaturated fatty acids
(PUFAs) in mitigating the significant morbidity and mortality caused by degenerative …

Cognitive decline in the elderly, particularly Alzheimer's disease (AD), is a major socio-
economic and healthcare concern. We review here the literature on one specific aspect of …

DHA is a key nutritional n-3 PUFA and needs to be supplied by the human diet. DHA is
found in significant amounts in the retinal and neuronal cell membranes due to its high …

Neuroketotherapeutics represent a class of bioenergetic medicine therapies that feature the
induction of ketosis. These therapies include medium-chain triglyceride supplements …

Brain development is a sequential anatomical process characterised by specific well-
defined stages of growth and maturation. One of the fundamental and necessary events in …