[HTML][HTML] Leishmania infections: Molecular targets and diagnosis

M Akhoundi, T Downing, J Votýpka, K Kuhls… - Molecular aspects of …, 2017 - Elsevier
Progress in the diagnosis of leishmaniases depends on the development of effective
methods and the discovery of suitable biomarkers. We propose firstly an update …

Leishmaniasis worldwide and global estimates of its incidence

J Alvar, ID Vélez, C Bern, M Herrero, P Desjeux… - PloS one, 2012 - journals.plos.org
As part of a World Health Organization-led effort to update the empirical evidence base for
the leishmaniases, national experts provided leishmaniasis case data for the last 5 years …

Vector biology meets disease control: using basic research to fight vector-borne diseases

WR Shaw, F Catteruccia - Nature microbiology, 2019 - nature.com
Human pathogens that are transmitted by insects are a global problem, particularly those
vectored by mosquitoes; for example, malaria parasites transmitted by Anopheles species …

Visceral leishmaniasis: Epidemiology, diagnosis, and treatment regimens in different geographical areas with a focus on pediatrics

S Scarpini, A Dondi, C Totaro, C Biagi, F Melchionda… - Microorganisms, 2022 - mdpi.com
Visceral Leishmaniasis (VL) is a vector-borne disease caused by an intracellular protozoa of
the genus Leishmania that can be lethal if not treated. VL is caused by Leishmania donovani …

Neglected tropical diseases in sub-Saharan Africa: review of their prevalence, distribution, and disease burden

PJ Hotez, A Kamath - PLoS neglected tropical diseases, 2009 - journals.plos.org
The neglected tropical diseases (NTDs) are the most common conditions affecting the
poorest 500 million people living in sub-Saharan Africa (SSA), and together produce a …

The role of natural products in drug discovery and development against neglected tropical diseases

PM Cheuka, G Mayoka, P Mutai, K Chibale - Molecules, 2016 - mdpi.com
Endemic in 149 tropical and subtropical countries, neglected tropical diseases (NTDs) affect
more than 1 billion people annually, including 875 million children in developing …

Global distribution maps of the leishmaniases

DM Pigott, S Bhatt, N Golding, KA Duda, KE Battle… - Elife, 2014 - elifesciences.org
The leishmaniases are vector-borne diseases that have a broad global distribution
throughout much of the Americas, Africa, and Asia. Despite representing a significant public …

The early interaction of Leishmania with macrophages and dendritic cells and its influence on the host immune response

D Liu, JE Uzonna - Frontiers in cellular and infection microbiology, 2012 - frontiersin.org
The complicated interactions between Leishmania and the host antigen-presenting cells
(APCs) have fundamental effects on the final outcome of the disease. Two major APCs …

The socioeconomic burden of parasitic zoonoses: global trends

PR Torgerson, CNL Macpherson - Veterinary parasitology, 2011 - Elsevier
Diseases resulting from zoonotic transmission of parasites are common. Humans become
infected through food, water, soil and close contact with animals. Most parasitic zoonoses …

Transmission, reservoir hosts and control of zoonotic visceral leishmaniasis

RJ Quinnell, O Courtenay - Parasitology, 2009 - cambridge.org
Zoonotic visceral leishmaniasis (ZVL) caused by Leishmania infantum is an important
disease of humans and dogs. Here we review aspects of the transmission and control of …