Dense reconstruction of synaptic connectivity requires high-resolution electron microscopy
images of entire brains and tools to efficiently trace neuronal wires across the volume. To …

Abstract In 1994, Burrill and Easter described the retinal projections in embryonic and larval
zebrafish, introducing the term “arborization fields”(AFs) for the retinorecipient areas. AFs …

The use of spectral information in natural light to inform behaviour is one of the oldest and
most fundamental abilities of visual systems. It long-predates animals' venture onto the land …

Understanding brain-wide neuronal dynamics requires a detailed map of the underlying
circuit architecture. We built an interactive cellular-resolution atlas of the zebrafish brain at 6 …

To track and control self-location, animals integrate their movements through space.
Representations of self-location are observed in the mammalian hippocampal formation, but …

Retinal ganglion cells (RGCs) form an array of feature detectors, which convey visual
information to central brain regions. Characterizing RGC diversity is required to understand …

Brain development is orchestrated by both innate and experience-dependent mechanisms,
but their relative contributions are difficult to disentangle. Here we asked if and how central …

Animals must adapt their behavior to survive in a changing environment. Behavioral
adaptations can be evoked by two mechanisms: feedback control and internal-model-based …

Direction-selective (DS) neurons compute the direction of motion in a visual scene. Brain-
wide imaging in larval zebrafish has revealed hundreds of DS neurons scattered throughout …

The dense reconstruction of neuronal wiring diagrams from volumetric electron microscopy
data has the potential to generate fundamentally new insights into mechanisms of …