Hepatocellular carcinoma surveillance—Utilization, barriers and the impact of changing aetiology

DQ Huang, AG Singal, F Kanwal… - Nature Reviews …, 2023 - nature.com
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide.
Surveillance for HCC is critical for early detection and treatment, but fewer than one-quarter …

Factors associated with rates of HBsAg seroclearance in adults with chronic HBV infection: a systematic review and meta-analysis

YH Yeo, HJ Ho, HI Yang, TC Tseng, T Hosaka… - Gastroenterology, 2019 - Elsevier
Background & Aims Seroclearance of hepatitis B surface antigen (HBsAg) is a marker for
clearance of chronic hepatitis B virus (HBV) infection, but reported annual incidence rates of …

Effects of tenofovir vs entecavir on risk of hepatocellular carcinoma in patients with chronic HBV infection: a systematic review and meta-analysis

WM Choi, J Choi, YS Lim - Clinical Gastroenterology and Hepatology, 2021 - Elsevier
Background & Aims Tenofovir disoproxil fumarate (TDF) and entecavir are recommended as
first-line treatments for chronic hepatitis B virus (HBV) infection. However, there is debate …

Similar risk of hepatocellular carcinoma during long-term entecavir or tenofovir therapy in Caucasian patients with chronic hepatitis B

GV Papatheodoridis, GN Dalekos, R Idilman… - Journal of …, 2020 - Elsevier
Background & Aims A recent study in Asian patients with chronic hepatitis B (CHB) reported
that the incidence of hepatocellular carcinoma (HCC) was lower in patients treated with …

Comparative effectiveness of entecavir versus tenofovir for preventing hepatocellular carcinoma in patients with chronic hepatitis B: a systematic review and meta …

S Dave, S Park, MH Murad, A Barnard, L Prokop… - …, 2021 - Wiley Online Library
Background and Aims Chronic hepatitis B (CHB) can lead to hepatocellular carcinoma
(HCC). While both tenofovir disoproxil (TDF) and entecavir (ETV) have been shown to …

long‐term safety of oral anti‐viral treatment for chronic hepatitis B

GLH Wong, WK Seto, VWS Wong… - Alimentary …, 2018 - Wiley Online Library
Background Safety profile of nucleos (t) ide analogues is an important issue in view of its
widespread use for decades in patients with chronic hepatitis B (CHB). Aim To review and …

Clinical utility of hepatocellular carcinoma risk scores in chronic hepatitis B

T Voulgaris, M Papatheodoridi, P Lampertico… - Liver …, 2020 - Wiley Online Library
Background Several risk scores have been recently developed to predict hepatocellular
carcinoma (HCC) in chronic hepatitis B (CHB) patients. We systematically assessed the …

Antiviral drugs and acute kidney injury (AKI)

W Leowattana - … -Drug Targets (Formerly Current Drug Targets …, 2019 - ingentaconnect.com
The introduction of more efficient antiviral drugs are common cause drug-induced acute
kidney injury (AKI). The true prevalence of antiviral drugs induced nephrotoxicity is hardly …

Hepatocellular carcinoma prediction models in chronic hepatitis B: a systematic review of 14 models and external validation

S Wu, N Zeng, F Sun, J Zhou, X Wu, Y Sun… - Clinical …, 2021 - Elsevier
Background & Aims The aim of our study was to characterize the performance of
hepatocellular carcinoma (HCC) prediction models in chronic hepatitis B (CHB) patients …

Long-term efficacy and safety of nucleos (t) ides analogues in patients with chronic hepatitis B

L Roade, M Riveiro-Barciela… - … in Infectious Disease, 2021 - journals.sagepub.com
Nucleos (t) ide analogues with high barrier to resistance are regarded as the principal
therapeutic option for chronic hepatitis B (CHB). Treatment with entecavir (ETV), tenofovir …