Colorectal cancer (CRC) is a heterogeneous disease of the intestinal epithelium that is
characterized by the accumulation of mutations and a dysregulated immune response. Up to …

The huge communities of residential microbes, including bacteria, viruses, Archaea, and
Eukaryotes, that colonize humans are increasingly recognized as playing important roles in …

Background Helicobacter pylori infection and a family history of gastric cancer are the main
risk factors for gastric cancer. Whether treatment to eradicate H. pylori can reduce the risk of …

Background Patients with early gastric cancers that are limited to gastric mucosa or
submucosa usually have an advanced loss of mucosal glandular tissue (glandular atrophy) …

Chronic infection with Helicobacter pylori cagA-positive strains is the strongest risk factor for
gastric cancer. The cagA gene product, CagA, is delivered into gastric epithelial cells via the …

Objectives To determine whether searching for Helicobacter pylori and treating with
eradication therapy leads to a reduction in incidence of gastric cancer among healthy …

Background & Aims Nearly all studies of gastric adenocarcinoma in the United States have
relied on national cancer databases, which do not include data on Helicobacter pylori …

Background Endometrial cancer studies have led to a number of well-defined but
mechanistically unconnected genetic and environmental risk factors. One of the emerging …

Gastric cancer has long been recognized to be accompanied and preceded by chronic
gastritis, lasting decades. Arguably, the most important development in our understanding of …

Nitric oxide (NO), is a ubiquitous, water soluble, free radical gas, which plays key role in
various physiological as well as pathological processes. Over past decades, NO has …