Diabetes mellitus: screening and diagnosis

K Pippitt, M Li, HE Gurgle - American family physician, 2016 - aafp.org
Diabetes mellitus is one of the most common diagnoses made by family physicians.
Uncontrolled diabetes can lead to blindness, limb amputation, kidney failure, and vascular …

Latent autoimmune diabetes in adults (LADA) should be less latent

S Fourlanos, F Dotta, CJ Greenbaum, JP Palmer… - Diabetologia, 2005 - Springer
Abstract 'Latent autoimmune diabetes in adults'(LADA) is the term coined to describe adults
who have a slowly progressive form of autoimmune or type 1 diabetes that can be treated …

Adult-onset autoimmune diabetes in Europe is prevalent with a broad clinical phenotype: Action LADA 7

MI Hawa, H Kolb, N Schloot, H Beyan… - Diabetes …, 2013 - Am Diabetes Assoc
OBJECTIVE Specific autoantibodies characterize type 1 diabetes in childhood but are also
found in adult-onset diabetes, even when initially non–insulin requiring, eg, with latent …

C-peptide is the appropriate outcome measure for type 1 diabetes clinical trials to preserve β-cell function: report of an ADA workshop, 21–22 October 2001

JP Palmer, GA Fleming, CJ Greenbaum, KC Herold… - Diabetes, 2004 - Am Diabetes Assoc
The underlying cause of type 1 diabetes, loss of β-cell function, has become the therapeutic
target for a number of interventions in patients with type 1 diabetes. Even though insulin …

Latent autoimmune diabetes in adults

RG Naik, BM Brooks-Worrell… - The Journal of Clinical …, 2009 - academic.oup.com
Context: Autoantibodies that are reactive to islet antigens are present at the time of
diagnosis in most patients with type 1 diabetes. Additionally, approximately 10% of …

First genome-wide association study of latent autoimmune diabetes in adults reveals novel insights linking immune and metabolic diabetes

DL Cousminer, E Ahlqvist, R Mishra… - Diabetes …, 2018 - Am Diabetes Assoc
OBJECTIVE Latent autoimmune diabetes in adults (LADA) shares clinical features with both
type 1 and type 2 diabetes; however, there is ongoing debate regarding the precise …

Latent autoimmune diabetes in adults: definition, prevalence, β-cell function, and treatment

G Stenstrom, A Gottsäter, E Bakhtadze, B Berger… - Diabetes, 2005 - Am Diabetes Assoc
Latent autoimmune diabetes in adults (LADA) is a disorder in which, despite the presence of
islet antibodies at diagnosis of diabetes, the progression of autoimmune β-cell failure is …

Etiology and pathogenesis of latent autoimmune diabetes in adults (LADA) compared to type 2 diabetes

S Carlsson - Frontiers in physiology, 2019 - frontiersin.org
As the heterogeneity of diabetes is becoming increasingly clear, opportunities arise for more
accurate assessment of factors influencing disease onset, which may lead to more efficient …

Genetic similarities between latent autoimmune diabetes in adults, type 1 diabetes, and type 2 diabetes

C Cervin, V Lyssenko, E Bakhtadze, E Lindholm… - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE—Latent autoimmune diabetes in adults (LADA) is often considered a slowly
progressing subtype of type 1 diabetes, although the clinical picture more resembles type 2 …

Type 1 diabetes and latent autoimmune diabetes in adults: one end of the rainbow

RDG Leslie, R Williams, P Pozzilli - The Journal of Clinical …, 2006 - academic.oup.com
Context: The aim of this review was to explore the pathogenic and clinical spectrum of type 1
diabetes, which includes a form of adult onset autoimmune diabetes usually referred to as …