Due to their bioactivity and harmful potential, advanced glycation end products (AGEs) are
discussed to affect human health. AGEs are compounds formed endogenously in the human …

Non-enzymatic protein glycosylation (glycation) contributes to many diseases and aging of
organisms. It can be expected that inhibition of glycation may prolong the lifespan. The …

Modern diets can cause modern diseases. Research has linked a metabolite of sugar,
methylglyoxal (MG), to the development of diabetic complications, but the exact mechanism …

Aging is a multifactorial process that involves changes at the cellular, tissue, organ and the
whole body levels resulting in decreased functioning, development of diseases, and …

Diabetic neuropathy is the most common and debilitating complication of diabetes mellitus
with more than half of all patients developing altered sensation as a result of damage to …

STUDY QUESTION Do advanced glycation end products (AGEs) and their receptors play a
role in female reproduction? SUMMARY ANSWER AGEs might contribute to the etiology of …

Oxidative stress can result in insulin resistance, a primary cause of type-2 diabetes.
Methylglyoxal (MG), a highly reactive dicarbonyl metabolite generated during glucose …

In recent years, glycative stress from exogenous or endogenous advanced glycation end
products (AGEs) and highly reactive dicarbonyls has gained great attention for its putative …

OBJECTIVE The incidence of high dietary carbohydrate-induced type 2 diabetes is
increasing worldwide. Methylglyoxal (MG) is a reactive glucose metabolite and a major …

Aldehydes are widespread in the environment, with multiple sources such as food and
beverages, industrial effluents, cigarette smoke, and additives. The toxic effects of exposure …