Context Positron emission tomography (PET) of 68 Ga-labelled prostate-specific membrane
antigen (68 Ga-PSMA) is an emerging imaging modality introduced to assess the burden of …

Currently, the findings of imaging procedures used for detection or staging of prostate
cancer depend on morphology of lymph nodes or bone metabolism and do not always meet …

Prostate cancer is the second most common malignancy in men worldwide and consists of a
mixture of tumor and non-tumor cell types. To characterize the prostate cancer tumor …

A comprehensive cellular anatomy of normal human prostate is essential for solving the
cellular origins of benign prostatic hyperplasia and prostate cancer. The tools used to …

Despite much recent progress, prostate cancer continues to represent a major cause of
cancer-related mortality and morbidity in men. Since early studies on the role of the …

The prostate-specific membrane antigen (PSMA) is highly expressed on most prostate
cancer (PC) cells. Therefore, the targeting of PSMA has become increasingly important over …

The murine Pten prostate cancer model described in this study recapitulates the disease
progression seen in humans: initiation of prostate cancer with prostatic intraepithelial …

TMPRSS2-ERG gene fusions are the predominant molecular subtype of prostate cancer.
Here, we explored the role of TMPRSS2-ERG gene fusion product using in vitro and in vivo …

Despite efforts to profile prostate cancer, the genetic alterations and biological processes
that correlate with the observed histological progression are unclear. Using laser-capture …

Accumulating evidence suggests that codeletion of the tumor suppressor genes Pten and
p53 plays a crucial role in the development of castration-resistant prostate cancer in vivo …