Experimental autoimmune encephalomyelitis (EAE) is the most commonly used
experimental model for the human inflammatory demyelinating disease, multiple sclerosis …

Intravenous immunoglobulin (IVIG) preparations comprise pooled IgG antibodies from the
serum of thousands of donors and were initially used as an IgG replacement therapy in …

Intravenous immunoglobulin (IVIG) is a pooled preparation of normal IgG obtained from
several thousand healthy donors. It is widely used in the immunotherapy of a large number …

Nearly 350 IgG-based therapeutics are approved for clinical use or are under development
for many diseases lacking adequate treatment options. These include molecularly …

We have identified at least 2 highly promiscuous major histocompatibility complex class II T-
cell epitopes in the Fc fragment of IgG that are capable of specifically activating CD4+ …

Intravenous immune globulin (IVIG) is an important treatment modality in patients with
humoral or B-cell immune deficiency as replacement therapy. Soon after its introduction in …

Immune and inflammatory responses actively modulate the pathophysiological processes of
acute brain injuries such as stroke. Soon after the onset of stroke, signals such as brain …

Childhood immune thrombocytopenia (ITP) is a rare autoimmune bleeding disorder. Most
children recover within 6 to 12 months, but individual course is difficult to predict. We …

High-dose intravenous immunoglobulin (IVIg) preparations are used currently for the
treatment of autoimmune or inflammatory diseases. Despite numerous studies …

Experimental autoimmune encephalomyelitis (EAE) is still the most widely accepted animal
model of multiple sclerosis (MS). Different types of EAE have been developed in order to …