Our sense of hearing depends on precisely organized circuits that allow us to sense,
perceive, and respond to complex sounds in our environment, from music and language to …

Two qualitatively different kinds of neural map have been described: continuous maps
exemplified by the visual retinotopic map, and discrete maps exemplified by the olfactory …

Theoretical neuroscience provides a quantitative basis for describing what nervous systems
do, determining how they function, and uncovering the general principles by which they …

Abstract Ephrin-A2 and-A5 are thought to be anteroposterior mapping labels for the
retinotectal/retinocollicular projection. Here, gene disruptions of both these ephrins are …

Topographic maps are a fundamental feature of sensory representations in nervous
systems. The formation of one such map, defined by the connection of ganglion cells in the …

The mammalian brain is the most complex organ in the body. It controls all aspects of our
bodily functions and interprets the world around us through our senses. It defines us as …

Topographic maps, in which the spatial order of neurons maps smoothly onto their axonal
target, are a central feature of neural wiring. Ephrins and Eph receptors are well accepted as …

Ephrin-As act as retinal topographic mapping labels, but the molecular basis for two key
aspects of mapping remains unclear. First, although mapping is believed to require …

The development of neural tissue is a complex organizing process, in which it is difficult to
grasp how the various localized interactions between dividing cells leads relentlessly to …

The development of the nervous system is an extremely complex and dynamic process.
Through the continuous interplay of genetic information and changing intra-and extracellular …