Extracellular vesicles: A bright star of nanomedicine

P Wu, B Zhang, DKW Ocansey, W Xu, H Qian - Biomaterials, 2021 - Elsevier
Extracellular vesicles (EVs) have unique structural, compositional, and morphological
characteristics as well as predominant physiochemical stability and biocompatibility …

Isolation of extracellular vesicles: general methodologies and latest trends

MY Konoshenko, EA Lekchnov… - BioMed research …, 2018 - Wiley Online Library
Background. Extracellular vesicles (EVs) play an essential role in the communication
between cells and transport of diagnostically significant molecules. A wide diversity of …

Microfluidics for exosome isolation and analysis: enabling liquid biopsy for personalized medicine

JC Contreras-Naranjo, HJ Wu, VM Ugaz - Lab on a Chip, 2017 - pubs.rsc.org
Exosomes, the smallest sized extracellular vesicles (∽ 30–150 nm) packaged with lipids,
proteins, functional messenger RNAs and microRNAs, and double-stranded DNA from their …

Progress in microfluidics‐based exosome separation and detection technologies for diagnostic applications

S Lin, Z Yu, D Chen, Z Wang, J Miao, Q Li, D Zhang… - Small, 2020 - Wiley Online Library
Exosomes are secreted by most cell types and circulate in body fluids. Recent studies have
revealed that exosomes play a significant role in intercellular communication and are closely …

The Yin and Yang of exosome isolation methods: conventional practice, microfluidics, and commercial kits

SZ Shirejini, F Inci - Biotechnology Advances, 2022 - Elsevier
Exosomes are a subset of extracellular vesicles released from various cells, and they can be
found in different bodily fluids. Exosomes have been utilized as biomarkers to diagnose …

Current status and outlook of advances in exosome isolation

W Liu, Z Ma, X Kang - Analytical and Bioanalytical Chemistry, 2022 - Springer
Exosomes are extracellular vesicles with a diameter ranging from 30 to 150 nm, which are
an important medium for intercellular communication and are closely related to the …

Label-free isolation of exosomes using microfluidic technologies

S Hassanpour Tamrin, A Sanati Nezhad, A Sen - ACS nano, 2021 - ACS Publications
Exosomes are cell-derived structures packaged with lipids, proteins, and nucleic acids. They
exist in diverse bodily fluids and are involved in physiological and pathological processes …

Exosome isolation: a microfluidic road-map

A Liga, ADB Vliegenthart, W Oosthuyzen, JW Dear… - Lab on a Chip, 2015 - pubs.rsc.org
Exosomes, first isolated 30 years ago, are nanoscale vesicles shed by most types of cells.
The nucleic acid rich content of these nanoparticles, floating in virtually all bodily fluids, has …

Recent microfluidic advances in submicron to nanoparticle manipulation and separation

S Hettiarachchi, H Cha, L Ouyang, A Mudugamuwa… - Lab on a Chip, 2023 - pubs.rsc.org
Manipulation and separation of submicron and nanoparticles are indispensable in many
chemical, biological, medical, and environmental applications. Conventional technologies …

A microfluidic ExoSearch chip for multiplexed exosome detection towards blood-based ovarian cancer diagnosis

Z Zhao, Y Yang, Y Zeng, M He - Lab on a Chip, 2016 - pubs.rsc.org
Tumor-derived circulating exosomes, enriched with a group of tumor antigens, have been
recognized as a promising biomarker source for cancer diagnosis via a less invasive …